The BLSA Home Visit Program

在本项目范围内开展的活动包括： 1.追踪并更新自1990年以来最后一次联系(面对面或通过电话)至少一次的终止但未正式退出参加研究的BLSA参与者的联系信息。 2.与符合条件的BLSA参与者进行电话联系，以确定参加BLSA诊所访问、参加家访计划或完成电话面试的当前状态和意愿。 3.建立一个跟踪、联系和跟踪妇女和儿童生活津贴参与者的正式程序，并执行一个将门诊和家访结合在一起并发挥互补作用的程序。 4.在参加家庭访问计划的BLSA参与者中，对健康状况进行广泛评估，旨在确定与健康相关的多种结果(痴呆症、行动受限、日常生活能力障碍、虚弱、冠心病、癌症等)。 5.在参加家庭访问计划的BLSA参与者中，采集血液样本，用于临床化学基础测试、细胞、血清和血浆的DNA提取和储存。 6.向参与者及其家人提供研究的详细说明，并就参与获得知情同意，包括同意使用以前收集的生物标本。 7.建立一个数据库，其中包括跟踪信息和通过电话面谈和当面家访收集的所有信息，同时保持与南部非洲发展组织核心数据库的完全兼容。

Activities conducted within the context of this project include: 1. Trace and update contact information for BLSA participants who discontinued but did not formally withdraw study participation who were last contacted (in person or over the telephone) at least once since 1990. 2. Make a telephone contact with eligible BLSA participants to establish current status and williness to attend a BLSA clinic visit, participate in the home visit program or complete a telephone interview. 3. Create a formal process for tracking, contacting and following BLSA participants, and implement a process in which in-clinic and home visits are integrated and serve complementary purposes. 4. In BLSA participants enrolled in the home visit program, conduct an extensive assessment of health status, aimed at ascertaining multiple health-related outcomes (dementia, mobility limitation, ADL disability, frailty, CHD, cancer, etc.). 5. In BLSA participants enrolled in the home visit program, collect a blood sample to be used for basic tests of clinical chemistry, DNA extraction and storage of cells, serum and plasma. 6. Provide participants and their families with a detailed description of the study, and obtain informed consent for participation, including consent for the use of previously collected biological specimens. 7. Create a database with tracking information and all information collected over the telephone interview and during in person home visits, maintaining full compatibility with the BLSA core database.