Administrative Core

instmctions）; 行政核心将负责监督方案的日常职能， 本项目的资助目标。核心小组将提供行政支助，包括赠款支助 和财务管理;安排会议和研讨会;协调本POI之间的活动 和加州大学洛杉矶分校的学术和行政机构，以及弗吉尼亚州大洛杉矶医疗保健系统-西部 洛杉矶。核心还将为所有研究项目和管理提供生物制药支持 研究数据和共享数据功能的程序。它将负责管理细节 适当地归档预算信息，并将提交进度报告和与 NCI计划，信息传播和项目研讨会的组织， 包括外部咨询委员会的参与，并监督所有既定的政策， 招募妇女和少数民族，以及与其他NCI计划的互动也将是责任 行政核心。行政核心，在博士的指导下。去吧，博士。 李刚将提供生物统计支持：研究项目有：项目1调查的重要性， 炎症对饮食诱导的胰腺癌发展的影响，并探讨前列腺素的作用 在这个过程中的信号，项目2探讨在细胞内信号传导过程中，是operafive在饮食， 诱导的胰腺癌发展以及鱼油（1）和二甲双胍（2）在饮食诱导的胰腺癌中的疗效 胰腺癌的发展，项目3将研究自噬的重要性，项目4是作用 在饮食诱导的胰腺癌发展中的结缔组织增生。所有项目都是一体化和协同增效的 并使用两个核心，管理核心（核心A）和动物核心（核心B）。这些项目也将使我们的 共享核心，包括NCCAM资助的加州大学洛杉矶分校胰腺疾病卓越中心，NDDK 支持消化疾病核心中心，NIAAA资助南加州酒精肝中心， 胰腺疾病，其他加州大学洛杉矶分校共享核心资源，以实现该计划项目的目标， 饮食诱导的Kras诱导的胰腺癌的促进作用。 相关性（参见说明）： 管理核心的目标是提供关键的管理职责来完成这一任务 项目的目标是在体内动物模型中研究其内在机制，为临床提供具体的 在胰腺癌的预防和治疗中的转化潜力和未来项目。

instmctions); The Administrative Core will be responsible for overseeing the daily functions of the programs in fulfilling the goal of this program project grant. The Core will provide administrative support, including support for grants and financial management; scheduling of meetings and seminars; coordination of activifies between this POI and UCLA academic and administrative bodies, and the VA Greater Los Angeles Healthcare System-West Los Angeles. The Core will also provide biostatisfical support for all research projects and the management of research data and shared data function of the program. It will have the responsibility of managing details of the budget, appropriately filing budgetary informafion, and will file progress reports and communicate with NCI. The scheduling, dissemination of information, and organization of the program project Symposium, including the participafion of the External Advisory Board, and oversight all of the established policies for recruitment of women and minorities, and interacfion with other NCI programs will also be the responsibilities of the Administrative Core. The Administrative Core, under the direcfion of Dr. Vay Liang W. Go and Dr. Gang Li will provide biostatistical support: The research projects are: Project 1 investigates the importance of inflammation on diet-induced pancreatic cancer development and explores the role of prostaglandin signaling in this process, Project 2 explores in the intracellular signaling processes that are operafive in diet- induced pancreatic cancer development and the efficacy of fish oil (1) and metformin (2) in diet-induced pancreatic cancer development, Project 3 will examine the importance of autophagy, and Project 4 is the role of desmoplasia in diet-induced pancreatic cancer development. All projects are integrated and synergisfic and utilize two Cores, an Administrative (Core A) and Animal Core (Core B). The projects will also ufilize our shared core, including those at NCCAM funded UCLA Center for Excellence in Pancreafic Diseases, NDDK supported Digestive Disease Core Center, NIAAA funded Southern California Center for Alcohol Liver and Pancreafic Disease, other UCLA shared core resources in fulfilling the program project's goal in targeting diet-induced promotion of Kras-induced pancreatic cancer. RELEVANCE (See instructions): It is the Administrative Core's goal to provide the key management responsibilities to accomplish this program project's goal in investigafing the underiying mechanism in vivo animal model, to provide specific translational potential and future projects in the prevention and treatment of pancreatic cancer.