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中文摘要
翻译
行政和分析核心将负责: 1)方案项目的所有行政方面,包括:i)方案的财务管理;ii) 协调和提交年度进展报告;三)与国家卫生研究院、IRB、IACUC、哥伦比亚联络 大学助学金和合同,以及环境健康和安全办公室。 2)方案项目的后勤支持,如:i)科学咨询之间的通信 委员会和计划,ii)为PI安排个人约会。 3)组织协调项目三大会议:一)月会 包括所有项目负责人、联合负责人、核心主管和关键人员;ii)年度务虚会 包括所有与会者和科学顾问;三)执行委员会会议。 4)生物统计学支持用小鼠和人体组织进行实验的设计和分析。 5)为基因表达和拷贝数的设计和分析提供生物统计学和生物信息学支持 来自人类肿瘤、小鼠肿瘤和组织培养实验的数据。 6)提供先进的基因组和系统生物学工具,用于详细分析转录和 翻译后调控通路及其在肿瘤分子表型研究中的应用 交互地图。 7)维护和更新网站,实现数据共享。
英文摘要
The Administrative and Analytical Core will be responsible for: 1) All administrative aspects of the program project including: i) financial management of the program; ii) coordination and submission of annual progress reports; iii) liaison with NIH, IRB, IACUC, Columbia University Grants & Contracts, and Environmental Health and Safety Offices. 2) Logistical Support of the program project, such as: i) correspondence between Scientific Advisory Committee and Program, ii) scheduling individual appointments for PI. 3) Organizing and coordinating the three major meetings of the program project: i) the monthly meeting including all project Leaders, co-Leaders, Core Directors, and key personnel; ii) the annual retreat that will include all participants and Scientific Advisors; iii) Executive Committee meeting. 4) Biostatistics support for the design and analysis of experiments with mice and human tissues. 5) Biostatistics and Bioinformatics support for the design and analysis of gene expression and copy number data from human tumors, mouse tumors and tissue culture experiments. 6) Provide advanced genomic and systems biology tools for a detailed analysis of the transcriptional and post-translational regulatory pathways and for the study of cancer phenotypes based on molecular interaction maps. 7) Maintain and update web site for data sharing.
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