Training Grant on the Biology of Aging

描述（由申请人提供）：拟议的项目代表了一项为期5年的机构培训补助金，该补助金包括来自UT圣安东尼奥健康科学中心（UTHSCSA） 7个学术部门的不同研究人员。申请资助10名博士预科生和6名博士后。美国即将出现的老年人雪崩，加上最近在了解老龄化基本机制方面取得的重大进展，对受过培训的研究人员产生了巨大的需求，这些研究人员需要研究延缓和缓解老龄化人口疾病的方法。UTHSCSA是衰老生物学的主要研究机构，拥有全国最大的师资队伍，其研究主要致力于衰老的基础生物学。提出的培训计划的主要目标是为研究生和博士后在衰老基础生物学研究领域的领导者做好智力准备。该培训项目涉及26名教职员工（16名男性，10名女性），并充分利用了紧密合作的员工所产生的协同效应，利用了我们的内森·肖克卓越衰老生物学中心提供的独特资源，以及对巴肖普研究所本身的机构承诺和不断扩大的资源。学员将根据他们的学术成就、对老龄化研究的兴趣和对研究事业的动机进行竞争。每个学员的主要活动是发展他们的教师监督的研究项目，由于我们教师之间的广泛合作，往往会产生令人惊讶的共同指导。受训者在双重指导下茁壮成长，我们现在已经将其制度化，作为我们培训计划的一个强制性特征。另一个关键组成部分是要求在我们的衰老生物学课程中获得广泛的衰老生物学知识，这样受训者就可以将他们的研究置于适当的科学背景中。除了这种正式的教学培训，我们还要求学员参加每周的老龄化研究杂志俱乐部，并参加每周的Barshop Institute系列研讨会和年度学员静修会。所有受训人员在进入我们的培训计划的前18个月内，都要完成为个别nrsa提供F系列拨款提案的拨款写作技巧培训。

DESCRIPTION (provided by applicant): The proposed program represents a 5-year continuation of an institutional training grant in the biology of aging, which was encompasses diverse investigators from 7 academic departments at UT Health Science Center San Antonio (UTHSCSA). We request funds to support 10 predoctoral and 6 postdoctoral trainees. The impending avalanche of elderly in the US combined with major recent advances in understanding fundamental mechanisms of aging has created a substantial demand for researchers trained to investigate means of delaying and relieving the ailments of an aging population. UTHSCSA is a premier research institution in the biology of aging, with the largest faculty in the country whose research is devoted primarily to the basic biology of aging. The primary goal of the proposed Training Program is to intellectually prepare both graduate students and postdoctoral fellows for careers as leaders in basic biological research in aging. The Training Program involves 26 faculty members (16 men, 10 women) and takes advantage of the synergies created by intensely collaborative personnel, the unique resources available from our Nathan Shock Center of Excellence in the Biology of Aging and the institutional commitment to, and expanding resources of, the Barshop Institute itself. Trainees will be chosen competitively based on academic excellence, their interest in aging research, and motivation for careers in research. The main activity of each trainee is the development of their faculty- supervised research project, which because of the extensive collaboration among our faculty tends to result surprisingly often in co-mentorships. Trainees have thrived with dual mentorships to the point that we have now institutionalized it as an obligatory feature of our training program Another key component is to require broad knowledge in the biology of aging acquired in our biology of aging course such that trainees' can place their research in an appropriate scientific context. In addition to this formal didactic training, we require trainees to attend the weekly Aging Research Journal Club and present at, as well as attend, our weekly Barshop Institute seminar series and annual trainee retreat. Training in grant writing skills resulting in an F- seris grant proposal for individual NRSAs are accomplished by all trainees within the first 18 months of entering our training program.