Training Program in Organogenesis

描述（由申请人提供）：生物医学科学在越来越多的转化方向上的快速发展要求我们确定策略，以帮助下一代科学家在复杂的研究环境中导航，在这种环境中，科学学科之间流畅的沟通和合作是成功的关键。密歇根大学器官发生中心成立于1995年，旨在将基础、应用和临床科学家联合起来，实现一个共同的目标：了解器官和组织形成和维持的基本机制，并利用这些知识创造持久的人造器官，改进干细胞疗法和有效的器官移植系统，以纠正人类获得性和遗传性疾病。14年前开始的器官发生培训计划是中心教育使命的一个组成部分。其目标是：a)提供器官发生领域的智力和技术培训；b)通过让受训者接触跨越临床、基础和应用科学界限的研究，促进跨学科思维。这些目标是通过鼓励研究培训的双导师结构和要求受训者参加几个具体的培训活动来实现的：器官发生的正式课程、器官发生研讨会系列、每月受训者会议、国际研讨会。学员们还积极塑造培训计划，提出了新的倡议，如生物艺术，艺术、科学和公共教育的新颖结合，以及相声，一个由一位临床科学家和一位基础科学家经营的临床案例论坛。此外，所有受训者都可以选择与临床联合导师配对，后者将促进他们对患者及其疾病的临床管理。这一竞争性更新要求支持5个博士预科和3个博士后培训名额（其中一个专门针对医学博士）。受训者主要来自培训计划列出的36位导师的实验室，他们都是备受认可的科学家。正式的竞争性申请，由选拔委员会审查，需要被任命参加培训计划。该计划由几个内部机制和两个外部顾问（杜克大学的Blanche Capel博士；辛辛那提儿童医院医疗中心的Christopher Wylie博士）监督，以确保其持续响应不断变化的研究环境的需求。

DESCRIPTION (provided by applicant): The rapid evolution of biomedical science in increasingly translational directions requires that we identify strategies to help the next generation of scientists navigate a complex research landscape in which fluent communication and collaboration between scientific disciplines is essential for success. The Center for Organogenesis at Michigan was formed in 1995 to unite basic, applied and clinical scientists with a common goal: To understand the basic mechanisms by which organs and tissues are formed and maintained, and to use this knowledge to create long-lasting artificial organs, improved stem cell therapies and effective organ transplantation systems that will correct acquired and genetic human diseases. The Training Program in Organogenesis, initiated 14 years ago, is an integral part of the educational mission of the Center. Its goals are: a) To provide intellectual and technical training in the field of organogenesis; and b) To promote interdisciplinary thinking by exposing trainees to research that crosses boundaries between the clinical, basic and applied sciences. These goals are accomplished by encouraging a two-mentor structure for research training and requiring trainees to participate in several specific training activities: a formal course in Organogenesis, Organogenesis Seminar series, Monthly Trainee Meeting, International Symposium. Trainees also actively shape the Training program, proposing new initiatives such as Bioartography, a novel combination of art, science and public education and Crosstalk, a clinical case-based forum run by one clinical and one basic scientist. Additionally, all trainees have the option to be paired with a clinical co-mentor who will facilitae their exposure clinical management of patients and their diseases. This competitive renewal requests support for 5 predoctoral and 3 postdoctoral training slots (one specifically targeted to an M.D. fellow). Trainees come primarily from the laboratories of the 36 listed mentors of the Training Program, all of whom are highly recognized scientists. Formal competitive applications, reviewed by a selection committee, are required for appointment to the Training Program. The Program is monitored by several internal mechanisms and also by two External Advisors (Dr. Blanche Capel, Duke University; Dr. Christopher Wylie, Cincinnati Children's Hospital Medical Center) to ensure its continued responsiveness to demands of a continuously evolving research environment.