Biostatistics, Epidemiology, and Research Design Core

生物统计学、流行病学和研究设计（BERD）关键组成活动（KCA）包括应用生物统计学、流行病学和信息学的先进方法来研究设计、实施和分析最先进的实验室、临床和社区研究。BERD通过俄克拉荷马共享临床和转化资源（OSCTR）向参与该提案的所有机构的学生、学员、教职员工和卫生保健专业人员提供专业知识、协作支持和培训。其中包括俄克拉何马大学健康科学中心（OUHSC）、俄克拉何马州诺曼大学、俄克拉何马州塔尔萨大学、俄克拉何马州医学研究基金会（OMRF）、退伍军人事务医疗中心、俄克拉何马州卫生部、奇卡索民族、切诺基民族、乔克托民族、俄克拉何马市印第安人诊所、南卡罗来纳医科大学、阿肯色大学健康科学中心和来自俄克拉何马州和堪萨斯州38个联邦承认的部落的美洲印第安部落健康中心。BERD的成员将把生物统计学、流行病学和信息学学科与其他OSCTR活动结合起来，促进疾病预防、诊断和治疗方法的发展和评估，以改善俄克拉荷马州和合作IDeA州的健康和健康结果。OSCTR的活动将包括基础医学实验室研究、临床前研究、随机对照临床试验、转化研究和社区研究，旨在提高对疾病过程及其相关风险因素的理解，评估创新诊断方法的有效性。评估潜在治疗方法的疗效和有效性，并在社区中加强最佳治疗和预防策略的采用。BERD KCA将以OUHSC生物统计和流行病学司和OMRF的现有努力为基础，在OSCTR中组织生物统计、流行病学和信息学资源。它将提供一个伞形组织，将生物统计学、流行病学和信息学方面的各种校园资源汇集到一个单一的实体中，从而加强这些努力。这种对研究设计和分析专业知识的集中关注将极大地促进研究质量、生产力和将研究成果转化为社区/人群中的实践。

The Biostatistics, Epidemiology, and Research Design (BERD) Key Component Activities (KCA) include the application of biostatistics, epidemiology and informatics advanced methods to the research design, conduct, and analysis of state-of-the-art laboratory, clinical and community-based studies. The BERD provides expertise, collaborative support and training through the Oklahoma Shared Clinical and Translational Resources (OSCTR) to students, trainees, faculty members and health care professionals at all of the institutions that are part of this proposal. Those include the seven colleges at the University of Oklahoma Health Sciences Center (OUHSC), OU-Norman, OU-Tulsa, Oklahoma Medical Research Foundation (OMRF), Veteran's Affairs Medical Center, Oklahoma State Health Department, Chickasaw Nation, Cherokee Nation, Choctaw Nation, Oklahoma City Indian Clinic, , Medical University of South Carolina, University of Arkansas Health Sciences Center and the American Indian tribal health centers from the 38 federally recognized tribes in Oklahoma and Kansas. Members of the BERD will integrate the disciplines of biostatistics, epidemiology, and informatics with other OSCTR activities to facilitate the development and evaluation of disease prevention, diagnosis, and treatment approaches to improve health and health outcomes in Oklahoma and partnering IDeA states. The OSCTR activities will include basic medical science laboratory research, preclinical studies, randomized controlled clinical trials, translational studies and community-based studies, which are aimed at improving the understanding of disease processes and their related risk factors, evaluating the validity of innovative diagnostic methods, estimating the efficacy and effectiveness of potential therapeutics and enhancing the adoption of best treatment and prevention strategies in the community. The BERD KCA will build on existing efforts of the OUHSC Department of Biostatistics and Epidemiology and OMRF to organize biostatistics, epidemiology and informatics resources in the OSCTR. It will enhance these efforts by providing an umbrella organization to bring together a diversity of campus resources in biostatistics, epidemiology, and informatics into a single entity. This concentrated focus of research design and analysis expertise will greatly facilitate research quality, productivity and the translation of research findings to practice in the community/population.