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Clinical Pharmacology & Analytical Chemistry Core

Clinical Pharmacology & Analytical Chemistry Core
临床药理学
批准号:
8708740
负责人:
Angela D Kashuba
金额:
$28.34万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
临床药理学和分析化学(CPAC)核心包含临床药理学专业知识,具有clia认证的实验室,以支持UNC, FHl和RTI的CFAR研究人员的临床和临床前艾滋病毒/艾滋病研究。由于CPAC核心是CFAR系统中唯一的一个,它也支持全国其他CFAR中越来越多的研究人员。CPAC核心由经验丰富的科学家组成,他们在试验设计、开发和验证复杂生物基质分析方法方面提供高水平的专业知识,以准确量化药物暴露,并解释临床前和临床药理学数据。该中心还在艾滋病毒预防战略、妇女健康问题和国际药理学方面发挥领导作用,并在药理学和分析方法方面培训国内和国际研究人员。
英文摘要
The Clinical Pharmacology and Analyfical Chemistry (CPAC) Core contains clinical pharmacology expertise with a CLIA-certified laboratory to support clinical and preclinical HIV/AIDS research among CFAR invesfigators at UNC, FHl, and RTI. Since the CPAC Core is the only one of its kind within the CFAR system, it also supports a growing number of invesfigators in other CFARs across the country. The CPAC Core consists of experienced scientists who provide a high level of expertise in trial design, development and validation of analytical methods in complex biological matrices to accurately quantify drug exposure, and interpretation of preclinical and clinical pharmacology data. The CPAC Core also provides leadership in HIV prevention strategies, women's health issues, and international pharmacology, and trains domestic and international investigators in pharmacologic and analytic methods.
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会议论文
Novel Mass Spectrometry Imaging Methods to Quantify Antiretroviral Adherence
Novel Mass Spectrometry Imaging Methods to Quantify Antiretroviral Adherence
Multi-Species Mechanisms of Drug Bio-distribution in HIV Tissue Reservoirs
Multi-Species Mechanisms of Drug Bio-distribution in HIV Tissue Reservoirs
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