BIOSTATISTICS

悉尼基梅尔综合癌症中心（SKCCC）生物统计共享资源（BiostatSR）包括6个博士级别的教员生物统计学家职位，其中一个正在填补中，4个硕士级别的统计学家和2个信息技术专家。BiostatSR成员在癌症相关临床、临床前、实验室和流行病学调查的设计、实施和分析方面与其他癌症中心研究人员进行合作和咨询。BiostatSR还在方案审查和监测系统-临床研究审查委员会（PRMS-CRC）中审查癌症相关临床研究的建议。生物统计学核心小组就研究设计（包括总体设计的有效性、实现目标的可行性、样本量和研究持续时间的预测）、关键基础设施（数据管理和计算机系统支持）的建议和发展、数据分析、报告准备和手稿撰写的协助，以及根据项目需要开发新的生物统计学方法提供咨询和专业知识。生物统计核心的目标是确保研究设计、数据监测和分析使用最先进的方法，并帮助中心支持的发展研究获得同行评审的资金。该中心在拨款周期内经历了教师的更替，其中大多数已成功更换，并计划在下一个拨款周期内进行教师和员工的控制增长。除了与中心的所有项目紧密结合外，核心生物统计学家与医疗机构中从事其他学科类似活动的其他专业人员有着重要的知识联系。这种多样化的环境为SKCCC研究人员提供了强大的、基础广泛的生物统计学专业知识，这些知识总是可以访问的。生物统计学的未来计划包括在信息系统倡议方面的合作，以支持临床和基础科学研究数据，以及在定量癌症研究中开发一个中心范围的项目。Lay：该核心在研究设计、关键基础设施的建议和发展、数据分析、报告准备和手稿撰写方面提供咨询和专业知识，并根据项目需要开发新的生物统计方法。癌症中心管理共享资源当前资助年度报告期：2010年1月1日至2010年12月31日。

DESCRIPTION OF SHARED RESOURCE The Sidney Kimmel Comprehensive Cancer Center (SKCCC) Biostatistics Shared Resource (BiostatSR) consists of six doctoral-level faculty biostatisticians positions, one of which is in the process of being filled, four master's level statisticians, and two information technology specialists. BiostatSR members collaborate and consult with other Cancer Center investigators in the design, conduct, and analysis of cancer-related clinical, preclinical, laboratory, and epidemiologic investigations. BiostatSR also reviews proposals for cancer-related clinical investigations in the Protocol Review and Monitoring System-Clinical Research Review Committee (PRMS-CRC). The Biostatistics Core provides consultation and expertise regarding study design (including validity of the overall design, feasibility of meeting objectives, sample size and projection of study duration), recommendations for and development of key infrastructure (data management and computer systems support), data analysis, preparation of reports and assistance with manuscript writing, and development of new biostatistical methods if required by the project. The goal of the Biostatistics Core is to ensure that study designs, data monitoring, and analyses use state-of-the-art methods, and to help developmental studies supported by the Center garner peer-reviewed funding. This Core has experienced turnover in faculty during the grant cycle, most of whom have successfully been replaced, with a plan to undergo controlled growth during the next grant cycle amongst both faculty and staff. In addition to being strongly integrated into all Programs in the Center, biostatisticians in the Core have important intellectual ties to other professionals in the medical institutions who are engaged in similar activities in other disciplines. This diverse environment provides SKCCC investigators with strong, broad-based biostatistical expertise that is always accessible Plans for the future of Biostatistics include collaboration in initiatives in information systems to support clinical and basic science research data, and development of a centerwide Program in quantitative cancer research. Lay: This Core provides consultation and expertise regarding study design, recommendations for and development of key infrastructure, data analysis, preparation of reports and assistance with manuscript writing, and development of new biostatistical methods if required by the project. Cancer Center Managed Shared Resource Current Grant Year Reporting Period: January 1, 2010 to December 31, 2010 .