Training in Vascular Biology and Medicine

描述(由申请者提供)：这是印第安纳大学医学院由印第安纳血管生物学和医学中心(ICVBM)主任、医学博士基思·L·马奇指导的名为“血管生物学和医学培训”的机构国家研究服务奖的续签申请。这一培训基金的主要重点是从跨学科的角度为来自多个参与部门的研究员提供血管生物学培训，特别强调将基本发现转化为临床研究和实践。科学界和临床界以及美国心脏协会和美国国立卫生研究院等国家组织都认识到血管生物学和医学综合项目的重要性和稀缺性。在印第安纳大学，在过去的7年里，我们开发了一个血管生物学和医学的多学科项目，由来自基础和临床部门的30名研究人员组成。我们为这些调查人员之间的合作创造了一个高度互动的环境。重要的是，我们有 开发了几个小组活动，使自己能够在一个健全的训练环境中：血管 生物学研讨会系列、血管杂志俱乐部和两个血管研究讨论小组，每个小组最初的目标都是最终提交PPG或UOL多名研究人员资助。因此，培训计划的一个关键优势是它提供了一个结构，将来自多个学科的科学家和受训人员连接到一个统一的计划中，专注于为新出现的初级教师提供必要的培训，以发展对血管生物学的凝聚力，并最终成功地建立独立的研究生涯。ICVBM T32自4年前成立以来，已经能够为8名博士后研究员提供研究奖学金。这些受训人员卓有成效，他们的工作在同行评议的期刊上发表了25篇文章。此外，在完成T32支持的5名受训人员中，2人接受了学术教职任命，1人获得了儿科心脏病学的第二个研究员职位，为在这一领域的学术生涯做准备。

DESCRIPTION (provided by applicant): This is a renewal application for an institutional National Research Service Award entitled "Training in Vascular Biology and Medicine" at the Indiana University School of Medicine under the direction of Keith L. March, MD, PhD, the Director of the Indiana Center for Vascular Biology and Medicine (ICVBM). The primary focus of this training grant is to provide vascular biology training to fellows from multiple participating Divisions and Departments, from an interdisciplinary perspective with a particular emphasis on translation of basic findings into clinical research and practice. The importance, as well as rarity, of an integrated program in vascular biology and medicine is recognized by both scientific and clinical communities, and by national organizations such as the American Heart Association, and National Institutes of Health. At Indiana University, over the past 7 years, we have developed a multidisciplinary program in Vascular Biology and Medicine, comprised of 30 investigators from basic as well as clinical departments. We have created a highly interactive environment for collaboration among these investigators. Importantly, we have developed several group activities which lend themselves to a robust training environment: a vascular biology seminar series, a vascular journal club, and two vascular research discussion groups, each of which was originally targeted toward the eventual submission of a PPG or UOl multi-investigator grant. Thus, a key strength of the training program is its provision of a structure linking scientists and trainees from multiple disciplines into a unified program, focused on providing the training necessary for emerging junior faculty to develop a cohesive view of vascular biology, and, ultimately, to be successful in establishing independent research careers. The ICVBM T32 has been able to provide research fellowships for 8 post-doctoral fellows since its funding 4 years ago. These trainees have been highly productive, and their work has resulted in 25 publications in peer-reviewed journals. Furthermore, of the 5 trainees who have completed their T32 support, 2 have accepted academic faculty appointments, and 1 has progressed to a second fellowship in Pediatric Cardiology in preparation for an academic career in this field.