Cellular Approaches to Tissue Engineering and Regeneration

描述(由申请者提供)：匹兹堡大学通过组织工程和再生细胞方法(CATER)培训计划，为我们的多学科和创新的再生医学博士前培训寻求持续支持。Cater项目结合了来自不同学科组的教师和研究专业知识，这些学科将组织工程与人类疾病和再生治疗的分子和细胞方法相结合。再生医学是一个真正的跨学科领域，汇集了来自人类生物学、工程学、医疗器械、材料科学、医学和应用技术的科学家，专注于人体组织的修复和替换。再生医学领域最重大的挑战之一是培养每一种有利学科的下一代专家，必须对这些学科进行培训，认识到成功开展再生医学所需的跨学科挑战和方法。为了解决这个问题，我们开发了餐饮博士前培训计划，以填补更传统的以科室为重点的研究培训计划中经常存在的空白。CATER培训计划的目标是为在人类疾病和损伤的再生医学领域建立一个富有成效和独立的职业生涯提供坚实的基础。这一目标是通过高度协调和指导的跨学科培训计划实现的，该计划跨越部门和学科，并结合必修和选修课程、研究和专门培训机会。我们的历史(10年的资金支持)证明，我们正在实现我们的培训目标，培养出成功的科学家。过去受训人员的职业选择基本上表明了他们的准备和需求，满足了学术界和业界再生医学领域专家的及时需求，概括了CATER计划成功的定义。随着CATER计划进入第10个年头，我们现在意识到再生医学领域的成熟，以至于各种技术都在寻求商业化，以进入有偿临床护理领域。随着我们提出未来五年的计划，我们将继续巩固我们的优势，同时拥抱当今再生医学不可或缺的及时概念和范例。我们在项目中不断发展的课程反映了这些令人兴奋的时代，并通过与临床和翻译科学研究所、库尔特计划和技术管理办公室的严格合作，体现了板凳到床边、学术创业和转化医学的众所周知的概念。因此，我们建议作为一个团队，通过CATER计划，通过协调、跨学科和严格的教学和研究培训，继续培训实践再生医学的新一代科学家。

DESCRIPTION (provided by applicant): The University of Pittsburgh seeks continued support for our multidisciplinary and innovative pre-doctoral training in Regenerative Medicine via Cellular Approaches to Tissue Engineering and Regeneration (CATER) training program. The CATER program combines faculty and research expertise from a diverse group of disciplines that combine tissue engineering with molecular and cellular approaches of therapies for human disease and regeneration. Regenerative medicine is truly an interdisciplinary field that brings together scientists from human biology, engineering, medical devices, material sciences, medicine and applied technologies to focus on the repair and replacement of human tissues. One of the most significant challenges in regenerative medicine is developing the next generation of experts in each of the enabling disciplines that must be trained cognizant of the cross-disciplinary challenges and approaches required for successful practice of regenerative medicine. To address this issue we developed the CATER pre-doctoral training program to fill the gaps that often exist in more traditional departmentally-focused research training programs. The goal of the CATER training program is to provide a solid foundation upon which to build a productive and independent career in regenerative medicine for human disease and injury. This goal is accomplished via a highly coordinated and mentored interdisciplinary training program that traverses departments and disciplines, and combines required and elective courses, research and specialized training opportunities. Our history (10-years of funding support) provides evidence that we are accomplishing our training objectives and generating successful scientists. The evolving definition of success for CATER program is recapitulated by the career choices of the past trainees that in essence demonstrates their preparedness and demand, fulfilling the timely need of experts in the area of regenerative medicine in both academics and industry. As CATER program moves into its 10th year, we now appreciate the maturation of the field of regenerative medicine such that a broad variety of technologies are seeking to be commercialized to cross into the area of reimbursable clinical care. As we propose the program for the next five years, we continue to build on our strengths and concurrently embrace the timely concepts and paradigms integral to regenerative medicine today. Our evolving curricula in the program reflects these exciting times and embodies the proverbial concepts of bench to bedside, academic entrepreneurship and translational medicine through rigorous partnerships with the Clinical and Translational Science Institute, the Coulter program and the Office of Technology Management. We thus propose to continue, as a team, train a new generation of scientists practicing regenerative medicine through coordinated, interdisciplinary and rigorous didactic and research training via the CATER program.