Genome Technologies

介绍 杰克逊实验室（J/\X）成立于1929年，是一个独立的非营利机构，致力于哺乳动物遗传学及其在精准医学中的应用的研究和教育，并通过获取我们的遗传资源来增强其他人在科学事业中的能力。JAX癌症中心（JAXCC）包括实验室的癌症研究和教育活动，以及用于癌症研究的机构共享资源。向外部研究社区提供小鼠的大规模分销殖民地由一个名为JAX Mice & Services的管理部门独立于JAXCC进行管理。分销殖民地在财政上是自给自足的，作为一个非营利组织，产生盈余，支持基础研究。 JAXCC占用三个JAX校园的设施，如下所述。JAX的主校区位于缅因州的巴尔港，占地约75万英尺[2]。我们已经启动了一个重大的扩张与康涅狄格州健康中心（UCHC）在法明顿，康涅狄格大学附近的校园开放。这个新的校园，称为杰克逊基因组医学实验室（JAX基因组医学），将是一个189，000英尺的设施，将于2014年完成。该校区的JAXCC成员专注于人类癌症基因组学，计算生物学及其在精准医学中的应用。第三个校区，位于加州萨克拉门托的JAX-West设施已经扩展到包括患者来源的异种移植（PDX）原发性人类癌症的大型协作资源，显著增强了JAXCC的癌症资源。位于巴尔港的原校区已更名为杰克逊哺乳动物遗传学实验室（JAX哺乳动物遗传学），以反映其在扩大的三校区框架内的作用。总的来说，我们有一个拥有卓越基础设施的机构，可以在哺乳动物遗传学方面进行创新和科学研究。校园的地理分布性质是我们的优势，能够利用当地（国家）的资源和人才，但统一的领导，组织，我们对遗传学和基因组学的关注。

Introduction The Jackson Laboratory (J/\X) founded in 1929, is an independent, nonprofit institute dedicated to research and education in mammalian genetics and its application to precision medicine, as well as to empowering others in their scientific enterprise through access to our genetic resources. The JAX Cancer Center (JAXCC) comprises the cancer research and education activities at the Laboratory, as well as institutional shared resources that are used in cancer research. The large-scale distribution colonies that supply mice to the external research community are managed independently from the JAXCC by an administrative arm called JAX Mice & Services. The distribution colonies are financially self-supporting and, as a not-for-profit organization, generate surpluses that support fundamental research. The JAXCC occupies facilities on three JAX campuses, described below. The main JAX campus is an ~ 750,000 ft[2] facility in Bar Harbor Maine. We have launched a major expansion with the opening of a campus adjacent to the University of Connecticut Health Center (UCHC) in Farmington, Connecticut. This new campus, called The Jackson Laboratory for Genomic Medicine (JAX Genomic Medicine), will be a 189,000 ft[2] facility, to be completed in 2014. JAXCC members on this campus focus on human cancer genomics, computational biology and their application for precision medicine. The third campus, the JAX-West facility in Sacramento, California¿has expanded to include a large, collaborative resource of patient-derived xenografted (PDX) primary human cancers, significantly enhancing the cancer resources ofthe JAXCC. The original campus in Bar Harbor has been renamed The Jackson Laboratory for Mammalian Genetics (JAX Mammalian Genetics) to reflect its role within the expanded three-campus framework. In total, we have an institution that has remarkable infrastructure to innovate and conduct science in mammalian genetics. The geographically distributed nature ofthe campuses is to our advantage in being able to capitalize on local (state) resources and talent, but unified by leadership, organization, and our focus on genetics and genomics.