Cerebrovascular Fellowship Training Program

描述（申请人提供）：项目概要/摘要我们的培训计划的总体目标是培训和指导来自神经病学和急诊医学学科的临床研究人员，他们将成为中风和脑血管疾病原因和治疗调查的合作领导者和临床试验研究者，或在严重缺乏服务的神经重症监护临床研究竞技场的临床研究人员。我们为期两年的培训计划包括在脑血管疾病和中风以及神经重症监护环境中的其他急性神经系统疾病领域的广泛NIH资助的T-2重点转化研究中的临床研究和试验的广泛实践经验。我们的计划包括密切的指导，在计划的第一年内选择具体的研究项目;在生物统计学，流行病学，临床试验，伦理学，信息学和定制的课程工作根据学员的研究重点;流行病学，病理生理学，卒中/脑血管疾病以及在神经重症监护环境中治疗的其他急性神经系统疾病的治疗和结局;与基础科学家及其正在进行的研究项目的良好互动，指导学员实现独立的学术生涯;以及在评估和治疗急性中风患者或需要神经重症监护的患者方面的独特培训。这种创新的多学科培训模式一直由NIH路线图倡导，最近由NIH资助的临床和转化科学与培训中心（CCTST）倡导。我们的培训计划由广泛的合作者和导师网络组成，这些合作者和导师已经在我们的毕业生中产生了学术生产力。培训吸引了在急性中风治疗和临床试验方法/管理、基因组学、出血性中风、中风和血管生理学的动物模型和体外模型、创伤性脑损伤、神经重症监护方法、神经流行病学、生物统计学、神经介入治疗方面拥有专业知识的教师（血管内和外科）、神经影像学、神经恢复、神经超声学、神经技术开发、结局研究、卒中预防、研究的伦理设计，符合HIPAA和数据库管理。我们的学员是两个独立的NINDS资助的中心网络（SPOTRIAS和NETT）的一部分，其中研究培训是一个主要目标。潜在的受训者必须完成神经病学或急诊医学的住院医师培训，并且必须证明对脑血管疾病和/或神经重症监护学术生涯的承诺;强调少数民族的招聘。

DESCRIPTION (provided by applicant): Project Summary / Abstract The overall goal of our training program is to train and mentor physician clinical researchers from the disciplines of neurology and emergency medicine who will become collaborative leaders and clinical trial investigators in the investigation of the causes and treatment of stroke and cerebrovascular disease or clinical researchers in the significantly underserved clinical research arena of neurocritical care. Our two-year training program includes extensive hands- on experience in clinical research and trials within a broad array of NIH-funded, T-2 focused, translational research in the area of cerebrovascular disease and stroke as well as other acute neurologic diseases in a neurocritical care setting. Our program includes close mentoring with selection of specific research projects within the first year of the program; well-defined course work in biostatistics, epidemiology, clinical trials, ethics, informatics, and customized course work based upon the trainees' research focus; lectures in the epidemiology, pathophysiology, treatment and outcome of stroke/cerebrovascular disease as well as other acute neurologic diseases treated in the neurocritical care setting; excellent interactions with basic scientists and their ongoing research projects, mentoring trainees in achieving an independent academic career; and unique training in the evaluation and treatment of patients with acute stroke or who require neurocritical care. This innovative and multi-disciplinary training model has been advocated by the NIH roadmap and more recently by the NIH-funded Centers for Clinical and Translational Science and Training (CCTST). Our training program is comprised of an extensive network of collaborators and mentors that has resulted in academic productivity among our graduates. Training draws on faculty with expertise in acute stroke therapy and clinical trial methodology/management, genomics, hemorrhagic stroke, animal models and in-vitro models of stroke and vascular physiology, traumatic brain injury, methods of neurocritical care, neuro- epidemiology, biostatistics, neuro-interventional therapy (endovascular and surgical), neuroimaging, neurorecovery, neurosonology, neurotechnology development, outcome research, stroke prevention, ethical design of research, HIPAA compliance, and data-base management. Our trainees are part of two separate NINDS-funded networks of centers (SPOTRIAS and NETT) in which research training is a major goal. Potential trainees must have completed a residency in neurology or emergency medicine and must demonstrate a commitment to an academic career in cerebrovascular disease and/or neurocritical care; minority recruitment is emphasized.