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中文摘要
翻译
圣安东尼奥是通往南得克萨斯州的门户,是美国最大的城市和最大的大都市区 西班牙裔人口占多数(63%)。南得克萨斯州大约有俄亥俄州那么大,由一个 贫困人口以西班牙裔为主,糖尿病和肥胖率不成比例, 由于缺乏医疗保险和获得医疗保健的机会很少,情况进一步恶化。该地区还包含 许多美国军事设施,以及现役军人和退伍军人往往有特殊的健康 这些问题包括增加患创伤后应激障碍和创伤损伤的风险。不幸的是, 无论是更好地获得医疗服务还是改善医疗服务,都不能消除健康差距并满足这些要求 复杂的需求。此外,需要对整个T L到T4的翻译谱进行研究,以消除 知识差距和建立现实世界的有效性,以改善我们人口的健康。 2006年,UTHSCSA成立了医学与科学整合研究所(IIMS),以改善 通过加速全面的科学发现和应用,实现健康和减少差距 翻译研究领域。例如,印度管理学院扩大了临床研究单位的数量, 从1个扩展到7个德克萨斯州-墨西哥边境,并显著增加了参与者获得临床和 翻译科学。我们将以实践为基础的研究网络从2个增加到6个 不同的流动人口。在过去5-10年内努力满足翻译科学员工的需求 年毕业100名临床调查硕士学生,资助19名成功的KL2学者, 并建立了新的联合翻译科学博士和证书课程。在这份提案中,我们提供 刺激临床和转化科学发展的战略,催化研究团队,并实施 培养具有创造性、协作性和文化多样性的科学家的项目。我们的具体目标是: 1.加快临床和转化性研究创新和有效的团队科学 通过提供与我们的战略计划相集成的学术之家,实现从T1到14的整个研究范围 合作机构。 2.扩大、多样化和加强跨学科转换生物医学的劳动力 科学家。 3.落实持续评估和优化服务的有效方法,提高 提高效率,改进流程,降低所有IIMs项目的成本。 相关性(见说明); 基于我们通过加速科学发现和改善南得克萨斯州健康状况的愿景 公共卫生应用,我们将部署战略资源,专注于我们的 区域,包括:1)我们服务不足的西班牙裔人口的健康需求,2)特殊的健康问题 面对现役军人和退伍军人群体,以及3)翻译科学劳动力的局限性 以填补关键的知识空白,改善南得克萨斯州和美国的健康状况。
英文摘要
San Antonio, the gateway to South Texas, is the 7"^ largest city in the US and the largest metropolitan area with a majority Hispanic population (63%). South Texas is about the size of Ohio, and comprises an impoverished and largely Hispanic population with disproportionate rates of diabetes and obesity, exacerbated by a lack of health insurance and poor access to health care. This region also contains numerous US military installations, and active-duty service members and veterans often have special health issues, including increased risk for post-traumatic stress disorder and traumatic injuries. Unfortunately, neither better access to care nor improved care delivery can eliminate health disparities and meet these complex needs. In addition, research across the full T l to T4 translational spectrum is required to eliminate knowledge gaps and establish real-world effectiveness that improves health cai^e for our populations. In 2006, UTHSCSA established the Institute for Integration of Medicine and Science (IIMS) to improve health and reduce disparities by accelerating scientific discoveries and applications across the full translational research spectrum. For example, IIMS expanded the number of clinical research units that extend to the Texas-Mexico border from 1 to 7, and dramatically increasing participant access to clinical and translational science. We increased, from 2 to 6, the Practice-Based Research Networks that focus on diverse ambulatory populations. Efforts to address translational science workforce needs over the past 5-10 years have graduated 100 Masters Clinical Investigation students, supported 19 successful KL2 Scholars, and established new joint Translational Science PhD and Certificate programs. In this proposal, we provide strategies to spur clinical and translational science evolution, catalyze research teams, and implement programs that produce creative, collaborative, and culturally diverse scientists. Our Specific Aims will: 1. Accelerate clinical and translational research innovation and effective team science along the entire T1 to 14 research spectrum by providing an academic home integrated with our strategic partner institutions. 2. Expand, diversify, and enhance the workforce of interdisciplinary translational biomedical scientists. 3. Implement effective methods to continuously evaluate and optimize services, increase efficiencies, improve processes, and reduce costs across all IIMS programs. RELEVANCE (See instructions); Based on our vision of improving the health status of South Texas by accelerating scientific discoveries and public health applications, we will deploy strategic resources that focus on prevalent challenges in our region, including: 1) the health needs of our underserved Hispanic population, 2) the special health issues facing active-duty military and veteran populations, and 3) limitations in the translational science workforce required to fill in critical knowledge gaps and improve health in South Texas and the US.
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Institute for Integration of Medicine & Science: A Partnership to Improve Health
Institute for Integration of Medicine & Science: A Partnership to Improve Health
Development of Sustainable Reporting to the National COVID Cohort Collaborative (N3C)
Institute for Integration of Medicine & Science: A Partnership to Improve Health
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: