Accelerating Autoimmune Treatments through Alopecia Areata Research
Accelerating Autoimmune Treatments through Alopecia Areata Research
批准号:
8969037
负责人:
DAVID A. NORRIS
金额:
$1.0万
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-09-01 至 2015-08-31
关键词:
AddressAffectAgeAlopecia AreataAmericanAnimal ModelAutoimmune DiseasesAutoimmune ProcessBiological ProductsClinical ResearchClinical TrialsCollaborationsComorbidityDermatologyDevelopmentDisabled PersonsDisciplineDiseaseEnsureEquilibriumEthnic OriginFamily memberFosteringFoundationsFundingFutureGeneticGenomicsGoalsGovernment AgenciesGrantHairHealthHearingHeredityImmune TargetingImmunologyInsulin-Dependent Diabetes MellitusKnowledgeLeadLearningLifeMethodsMinorityMissionMonitorNonprofit OrganizationsParticipantPatientsPhototherapyProcessPublic HealthPublished CommentPublishingRaceRegistriesResearchResearch DesignResearch PersonnelResearch PriorityResearch Project GrantsResearch ProposalsResearch SupportRiskSeasonsSeriesTalentsTestingTimeUnited States National Institutes of HealthVoiceWomanbasecareerclinical investigationdisease natural historyimprovedinnovationmedical specialtiesmeetingsposterspsychologicsocial
中文摘要
描述(由申请人提供):斑秃是一种以脱发为特征的疾病,影响650万所有年龄、种族和民族的美国人。 它更频繁地发生在那些影响家庭成员的人身上,这表明遗传和遗传是疾病发生的一个因素。 这一疾病的深刻影响是身体、社会和心理上的。 国家斑秃基金会(NAAF)是一个非营利组织,支持研究,以找到斑秃的治愈或可接受的治疗方法,支持那些患有这种疾病,并教育公众有关斑秃。 本次峰会是该基金会研究使命的核心:汇集来自世界各地相关专业的研究人员,从以往的研究进展中提取知识,并确定未来的优先事项。 NAAF使用这些优先级来评估研究提案并做出拨款决定。 长期目标是安全,有效,负担得起的治疗或治愈斑秃。本次研究峰会计划于2014年12月4日至5日在马里兰州贝塞斯达举行。 峰会将汇集代表遗传学,免疫学,相关自身免疫性疾病如1型糖尿病,皮肤病学和其他领域,包括光疗受人尊敬的研究人员。 首脑会议的目标是:1)复习新知识; 2)确定并优先考虑有希望的新的研究需求; 3)制定计划并促进伙伴关系;以及4)发布会议结果以分享发现。 包容妇女、少数民族和残疾人是
因此,我们利用广泛而平衡的知识领域。 我们鼓励早期职业调查员加入我们,带来新的想法和新的人才。 与会者与斑秃将
确保在确定优先顺序的过程中听取和考虑患者的意见。这次研究峰会的设计是两天,结合了一系列简短的演讲和广泛的讨论,每个参与者都有一个麦克风。 高级研究人员定期总结主要研究结果,联合主席将带领演讲者和与会者共同分析研究结果,并建议新的研究重点和伙伴关系。 我们的方法使研究人员能够听到跨多个学科的发现,并参与实质性的问答和讨论,促进创新和合作。
英文摘要
DESCRIPTION (provided by applicant): Alopecia areata is a disease characterized by hair loss that affects 6.5 million Americans of all ages, races and ethnicities. It occurs more frequently in people who have affected family members, suggesting heredity and genetics are a factor in disease occurrence. The profound effects of the disease are physical, social and psychological. The National Alopecia Areata Foundation (NAAF) is a nonprofit organization that supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata. This summit is central to the research mission of the Foundation: bringing together investigators from relevant specialties around the world to distill learning from previous research advances and determine future priorities. NAAF uses these priorities to evaluate research proposals and make grant funding decisions. The long-term objective is a safe, effective, affordable treatment or a cure for alopecia areata. This research summit is planned for December 4-5, 2014 in Bethesda, MD. The summit will bring together esteemed researchers representing genetics, immunology, related autoimmune diseases like type 1 diabetes, dermatology and other fields including phototherapy. Summit objectives are to: 1) review new knowledge; 2) identify and prioritize promising new needed research; 3) develop plans and facilitate partnerships; and 4) publish meeting results to share findings. Inclusion of women, minorities, and people with disabilities is
a priority so we draw on a broad and balanced field of knowledge. We encourage early-career investigators to join us and bring fresh ideas and new talent. Attendees with alopecia areata will
ensure that the patient perspective is heard and considered in the prioritization process. The design of this research summit is two days combining a series of short presentations with expansive discussion facilitated by each participant having a microphone. Key findings are periodically summarized by senior researchers and co-chairs will lead presenters and participants to collectively analyze findings and recommend new research priorities and partnerships. Our method of enabling researchers to hear findings across multiple disciplines and engage in substantive Q&A and discussion fosters innovation and collaboration.
期刊论文(17)
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Eosinophilic Esophagitis: Another Atopy-Related Alopecia Areata Trigger?
嗜酸性粒细胞性食管炎:另一种与特应性相关的斑秃触发因素?
DOI:
10.1038/jidsymp.2015.43
发表时间:
2015
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Ibrahim,Omer, Bergfeld,WilmaF, Piliang,Melissa]
通讯作者:
Piliang,Melissa
DOI:
10.1038/jidsymp.2015.41
发表时间:
2015-11-01
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Hordinsky, Maria K]
通讯作者:
Hordinsky, Maria K
Overview of AA and Research Progress: What Have We Learned and Where Are We Headed?
AA 概述和研究进展:我们学到了什么以及我们将走向何方?
DOI:
10.1038/jidsymp.2015.30
发表时间:
2015
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Norris,DavidA]
通讯作者:
Norris,DavidA
DOI:
10.1038/jidsymp.2015.38
发表时间:
2015-11-01
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Frelinger, Jeffrey A]
通讯作者:
Frelinger, Jeffrey A
DOI:
10.1038/jidsymp.2015.28
发表时间:
2015-11-01
期刊:
The journal of investigative dermatology. Symposium proceedings
影响因子:
--
作者:
[Chiang, Katherine S, Mesinkovska, Natasha A, Bergfeld, Wilma F]
通讯作者:
Bergfeld, Wilma F
共 17 条
Accelerating Autoimmune Treatments through Alopecia Areata Research
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Molecular Analysis, Modeling and Correction of Skin Diseases
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Melanoma Resistance to Apoptosis: Mechanisms and Therapeutic Potential
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