Biostatistics/Medical Informatics

生物统计学和医学信息学核心将由Alan Hutson博士和Carmelo Gaudioso博士领导。Hutson博士是Roswell Park癌症研究所（RPCI）的生物统计学和生物信息学主席，以及布法罗大学（UB）的生物统计学主席。他在基础、转化和临床实验设计和分析方面拥有20年的经验。Gaudioso博士是RPCI的医学信息学主任、临床数据网络副主任和肿瘤学助理教授。他的研究领域是知识管理和决策支持系统。 生物统计学和医学信息学核心将确保生物统计学，生物信息学和医学信息学设计和建模支持可用于所有RPCI前列腺癌SPORE项目负责人和核心主任及其合作研究者。生物统计学和医学信息学核心旨在提供统计支持，同时考虑机构的邻近性和个体研究者的生物统计学，生物信息学和医学信息学需求。具体而言，我们的目标是：通过应用适当的生物统计学和生物信息学分析，协助RPCI卵巢癌孢子的基础、转化和临床研究人员正确制定、完善和执行研究目标，并在优势和局限性方面对其结果进行适当解释;建立一个强大的数据管理系统，以有效管理卵巢癌孢子的信息学需求，支持多学科，多项目，多机构临床和转化研究，促进数据共享和信息传播;以及在数据足够成熟时通知RPCI-UPCI卵巢癌SPORE研究者撰写手稿，撰写手稿的统计方法部分，并在制定手稿的其余部分时提供专家协作指导。预计与SPORE相关的所有研究人员将广泛使用生物统计学和医学信息学核心的服务。生物统计学和医学信息学核心的好处包括提供一个致力于高效和有效协作的一致团队。开发生物统计学和医学信息学核心的好处包括提供一个一致的团队，致力于在三个综合癌症中心之间进行高效合作。

The Biostatistics and Medical Informatics Core will be led by Drs. Alan Hutson and Carmelo Gaudioso. Dr. Hutson is Chair of Biostatistics and Bioinformatics at Roswell Park Cancer Institute (RPCI) and Chair of Biostatistics at the University at Buffalo (UB). He has two decades of experience in basic, translational and clinical experimental design and analysis. Dr. Gaudioso is the Director of Medical Informatics, Associate Director of the Clinical Data Network, and Assistant Professor of Oncology at RPCI. His research area is knowledge management and decision support systems. The Biostatistics and Medical Informatics Core will ensure that biostatistics, bioinformatics and medical informatics design and modeling support is available to all RPCI Prostate Cancer SPORE project leaders and core directors and their co-investigators. The Biostatistics and Medical Informatics Core is designed to provide statistical support that considers both institutional proximity and the biostatistical, bioinformatics and medical informatics needs of individual investigators. Specifically, we aim to: To assist basic, translational and clinical researchers of the RPCI Ovarian Cancer SPORE with proper formulation, refinement and execution of study objectives by applying the appropriate biostatistics and bioinformatics analyses, and providing the appropriate interpretation of their results, in terms of both strengths and limitations; To establish a robust data management system to effectively manage the Ovarian Cancer SPORE's informatics needs in supporting multidisciplinary, multi-project, multi-institutional clinical and translational research and facilitating data sharing and information dissemination; and To notify RPCI-UPCI Ovarian Cancer SPORE investigators when data are sufficiently mature to write a manuscript, to write the statistical methods section of manuscripts and to provide expert collaborative guidance in formulating the rest of the manuscript. It is anticipated that the services of the Biostatistics and Medical Informatics Core will be extensively used by all researchers associated with the SPORE. Benefits to the Biostatistics and Medical Informatics Core include providing a consistent team dedicated to efficient and effective collaboration. Benefits towards developing the Biostatistics and Medical Informatics Core include providing a consistent team dedicated to efficient collaboration across three comprehensive cancer centers.