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中文摘要
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摘要 生物力学研究核心,以下称为生物力学核心,(BC)将使其人员 投入时间协助和培训研究人员进行新的和扩大的研究如何代谢 疾病和炎症与年龄相关疾病相互作用,确定与以下方面相关的关键健康结果 活动和功能状态,衰老的生物力学,以及老年医生和其他人的培训 与活动能力受损、跌倒和跌倒相关的损伤、尿失禁相关的生物力学的临床医生 以及老年人的脱垂。它们还将使核心支持的调查人员能够大量使用 机械系生物力学研究实验室现有设备和设施 工程,以及老年医学中心移动研究实验室的设施。 本请求寻求实现几个未实现的目标,整合新的想法,并扩大核心 活动进入新的领域。这些包括虚弱的老年人走路的精力,失去平衡和摔倒 老年女性有尿失禁、脱垂和大便失禁。经济效益是 通过此核心结构在设备和服务方面获得收益,而不是复制单独的 每一个都有生物力学部分。自成立以来,核心一直是为教职员工提供咨询服务 对老年人行动不便问题进行多学科研究。因此,它提供的建议可能会 否则,如果它不存在,就更难获得。这种一致性反过来又对质量产生积极的影响 在研究所进行的研究与同行评议出版物的记录相符, 成功的青年研究人员,并授予K12、K23、R21、R01和SCOR(P50)奖助金。
英文摘要
Abstract The Biomechanics Research Core, henceforth called the “Biomechanics Core,” (BC) will enable its personnel to devote time to assist and train investigators in the conduct of new and expanded research on how metabolic disease and inflammation interact with age-related disease to determine key health outcomes related to mobility and functional status, the biomechanics of aging, and to the training of geriatric physicians and other clinicians in the biomechanics relevant to impaired mobility, falls and fall-related injuries, urinary incontinence and prolapse in the elderly. They also will enable substantial use by Core-supported investigators of the equipment and facilities that exist in the Biomechanics Research Laboratory of the Department of Mechanical Engineering, as well as facilities in the Mobility Research Laboratory at the Geriatrics Center. The present request seeks to accomplish several unmet goals, integrate new ideas, and to broaden the Core activities into new areas. These include the energetics of walking in frail elderly, losses of balance and falls in the elderly, urinary incontinence, prolapse and fecal incontinence in older women. Economic efficiencies are gained in terms of equipment and service through this core structure rather than duplicating separate biomechanics components to each. Since its inception, the Core has served as a consulting service to faculty performing multidisciplinary research into geriatric mobility problems. It has thus provided advice which might otherwise be harder to obtain if it did not exist. This consistency in turn impacts in a positive sense the quality of the research conducted at the Institution as witnessed by the record of peer-reviewed publications, successful young investigators, and the K12, K23, R21, R01, and SCOR (P50) grants awarded.
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Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
  • 批准号:
    10217124
  • 项目类别:
  • 资助金额:
    $112.79万
  • 财政年份:
    2019
  • 负责人:
    JAMES Anthony ASHTON-MILLER
  • 依托单位:
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
  • 批准号:
    10019378
  • 项目类别:
  • 资助金额:
    $116.33万
  • 财政年份:
    2019
  • 负责人:
    JAMES Anthony ASHTON-MILLER
  • 依托单位:
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
  • 批准号:
    10449216
  • 项目类别:
  • 资助金额:
    $113.51万
  • 财政年份:
    2019
  • 负责人:
    JAMES Anthony ASHTON-MILLER
  • 依托单位:
Development of 21st Century Concepts and Tools for Quantifying Urethral Failure Mechanisms that Cause Urinary Incontinence
  • 批准号:
    9815669
  • 项目类别:
  • 资助金额:
    $122.52万
  • 财政年份:
    2019
  • 负责人:
    JAMES Anthony ASHTON-MILLER
  • 依托单位:
海外基金