Institute for Clinical and Translational Science

三年前，UCI创建了临床和翻译科学研究所(ICTS)，该研究所确定了 测试并实施创新方法，以打破阻碍生物医学发现的障碍。在下一个 在我们共同努力改造UCI临床研究企业的阶段，我们的愿景是：1)培养 新颖的协作-ICTS建立了多学科研究团队，如化学家和临床医生 探索人类“呼吸系统”中的呼吸生物标记物。团队科学领域的信息和通信技术专家将提供帮助 新的合作伙伴关系，以确定并消除成功协作的障碍 不可逾越。2)创造翻译科学的新技术--ICTS创造了基于UCI的新技术 生物光子学和微型设备等技术可供新一代临床医生使用。我们现在就会 通过与UCI信息科学家合作，开发和提供新的方法 用于实地研究的无处不在的计算；与护理和社会科学家进行定性和比较 有效性研究；以及与运动生理学家和分子生物学家的技术联系 具有动态疾病表型的基因组信息。3)共享信息--ICTS已与 临床医生、医院IT人员和信息与计算机科学学院的学者共同创建 生物医学信息学中心。我们现在已经准备好嵌入用于临床数据互操作的基础设施 在一个独特的时刻，即当UCI开始部署其EMR时；4)与我们的社区-ICTS 倡导新的方法，如PEER(研究中的参与者体验增强)计划 它将研究志愿者视为发现过程中的合作伙伴。我们计划了一系列 外展/传播活动，从减少虐待老年人到预防儿科猝死 运动员。和5)培训-我们将实施Crossing BoLindary，一套学位和证书计划 以及导师互动，解决翻译科学中的关键问题。最后，我们认为我们自己 作为南加州独特的翻译科学网络的一部分，在该网络中，区域资源 学术医疗中心被整合，以更好地实现CTSA的总体愿景。 相关性(请参阅说明)： UCI正在成为南加州这一充满活力的地区临床研究的推动力。这个 信息和通信技术将支持一系列有益于公共卫生的项目，包括雄心勃勃的美国国立卫生研究院资助的 国家儿童研究；对罕见的、研究较少的线粒体起源疾病的研究；以及社区 开展外展工作，以减轻本区域保险不足人群中肥胖造成的健康后果。

Three years ago, UCI created the Institute for Clinical and Translational Science (ICTS), which identifies tests, and implements innovative ways to break down barriers that impede biomedical discovery. In the next phase of our concerted effort to transform the UCI clinical research enterprise, our vision is to: 1) Nurture Novel Collaborations-The ICTS builds multidisciplinary research teams, such as chemists and clinicians exploring breath biomarkers in the human "ventilome." ICTS experts in the science of team science will help new partnerships to identify and remove obstacles to successful collaboration before they become insurmountable. 2) Create New Technologies for Translational Science-^The ICTS made novel UCI-based technologies such as biophotonics and microdevices available to a new generation of clinicians. We will now develop and provide new methodologies by partnering with UCI information scientists in the use of ubiquitous computing for field research; with nursing and social scientists for qualitative and comparative effectiveness research; and with exercise physiologists and molecular biologists for technologies that link genomic information with dynamic disease phenotypes. 3) Share Information-The ICTS has engaged clinicians, hospital IT staff, and scholars from the School of Information and Computer Sciences to create the Center for Biomedical Informatics. We are now ready to embed infrastructure for clinical data interoperability at a unique moment, namely, as UCI begins to deploy its EMR; 4) Engage Our Community-The ICTS championed new approaches such as PEER (Participant Experience Enhancement in Research), a program that views research volunteers as partners in the process of discovery. We plan a range of outreach/dissemination activities, from mitigating elder abuse to preventing sudden death in pediatric athletes. And 5) Train-^We will implement Crossing BoLindaries, a set of degree and certificate programs along with mentorship interaction that tackles key issues in translational science. Finally, we view ourselves as part of a unique translational science network for Southern California, in which the resources of regional academic medical centers are integrated to better realize the overarching vision of the CTSA. RELEVANCE (See instructions): UCI is becoming a motivating force for clinical research in this dynamic region of Southern California. The ICTS will support a wide range of projects that will benefit public health, including the ambitious NIH-funded National Childen's Study; research into rare, poorly studied diseases of mitochondrial origin; and community outreach efforts to mitigate the health consequences of obesity among underinsured people in our region.