Institute for Clinical and Translational Science

三年前，UCI创建了临床和转化科学研究所（ICTS）， 测试和实施创新方法，以打破阻碍生物医学发现的障碍。未来 在我们共同努力改造UCI临床研究企业的第一阶段，我们的愿景是：1）培养 新型合作-ICTS建立多学科研究团队，如化学家和临床医生 探索人类呼吸生物标志物的“麻烦”。“团队科学方面的ICTS专家将帮助 建立新的伙伴关系，以确定和消除成功合作的障碍， 无法克服的2)为转化科学创造新技术--基于UCI的新型ICTS 新一代临床医生可以使用的生物光子学和微型设备等技术。我们现在将 通过与UCI信息科学家合作，开发和提供新的方法， 无处不在的计算领域的研究;与护理和社会科学家进行定性和比较 有效性研究;以及与运动生理学家和分子生物学家合作， 基因组信息与动态疾病表型。3)分享信息-ICTS已参与 临床医生，医院IT人员，以及来自信息和计算机科学学院的学者， 生物医学信息学中心。我们现在已经准备好为临床数据互操作性嵌入基础设施 在一个独特的时刻，即UCI开始部署其EMR; 4）参与我们的社区-ICTS 支持新的方法，如PEER（参与者体验增强研究），一个计划， 将研究志愿者视为发现过程中的合作伙伴。我们计划一系列 外联/传播活动，从减少虐待老年人到预防儿童猝死 运动员培训-我们将实施跨越边界，一套学位和证书课程 沿着解决转化科学关键问题的导师互动。最后，我们认为自己 作为南加州独特的转化科学网络的一部分， 整合学术医疗中心，以更好地实现CTSA的总体愿景。 相关性（见说明）： UCI正在成为南加州这个充满活力的地区临床研究的动力。的 ICTS将支持一系列有利于公共卫生的项目，包括由NIH资助的雄心勃勃的 国家儿童研究;对罕见的、研究不足的线粒体起源疾病的研究;以及社区 开展外联工作，以减轻本区域保险不足人群中肥胖症对健康造成的后果。

Three years ago, UCI created the Institute for Clinical and Translational Science (ICTS), which identifies tests, and implements innovative ways to break down barriers that impede biomedical discovery. In the next phase of our concerted effort to transform the UCI clinical research enterprise, our vision is to: 1) Nurture Novel Collaborations-The ICTS builds multidisciplinary research teams, such as chemists and clinicians exploring breath biomarkers in the human "ventilome." ICTS experts in the science of team science will help new partnerships to identify and remove obstacles to successful collaboration before they become insurmountable. 2) Create New Technologies for Translational Science-The ICTS made novel UCI-based technologies such as biophotonics and microdevices available to a new generation of clinicians. We will now develop and provide new methodologies by partnering with UCI information scientists in the use of ubiquitous computing for field research; with nursing and social scientists for qualitative and comparative effectiveness research; and with exercise physiologists and molecular biologists for technologies that link genomic information with dynamic disease phenotypes. 3) Share Information-The ICTS has engaged clinicians, hospital IT staff, and scholars from the School of Information and Computer Sciences to create the Center for Biomedical Informatics. We are now ready to embed infrastructure for clinical data interoperability at a unique moment, namely, as UCI begins to deploy its EMR; 4) Engage Our Community-The ICTS championed new approaches such as PEER (Participant Experience Enhancement in Research), a program that views research volunteers as partners in the process of discovery. We plan a range of outreach/dissemination activities, from mitigating elder abuse to preventing sudden death in pediatric athletes. And 5) Train-We will implement Crossing Boundaries, a set of degree and certificate programs along with mentorship interaction that tackles key issues in translational science. Finally, we view ourselves as part of a unique translational science network for Southern California, in which the resources of regional academic medical centers are integrated to better realize the overarching vision of the CTSA. RELEVANCE (See Instructions): UCI is becoming a motivating force for clinical research in this dynamic region of Southern California. The ICTS will support a wide range of projects that will benefit public health, including the ambitious NIH-funded National Childen's Study; research into rare, poorly studied diseases of mitochondrial origin; and community outreach efforts to mitigate the health consequences of obesity among underinsured people in our region.