Research Facilities Restoration Program Alexandria Center for Life Sciences-West

描述(由申请人提供)：NYULMC是纽约市领先的医疗保健、生物医学研究、教育和公共服务中心。飓风桑迪对NYULMC研究基础设施造成了灾难性的破坏。因此，两个动物设施--Smilow Cellar vivarum和医学科学大楼(MSB)的Varium，以及位于MSB的一层基础科学实验室空间--无法用于研究。这项申请的目的是修复啮齿动物屏障住房、大型动物住房和手术室、ABSL-3设施和一层实验室空间。此外，在飓风发生时，由国家卫生研究所资助的20国集团翻修赠款(RR-030901)正在MSB间隔室进行。由于MSB间隔室不再适用于动物研究，这项申请的目的也是为了恢复G20的一些目标。拟议的建设将在地面以上的ACLS西塔进行，毗邻NYULMC主校区。NYULMC与ACLS签订了租约，租期为入住后20年。更换研究基础设施将能够支持调查人员，目前的年度在役经费总额为82 345 944美元，待批研究补助金为118 213 845美元。本申请中概述的项目是我们恢复过程中不可或缺的组成部分，将恢复当前研究人员进行研究所需的绝对关键的动物和实验室设施，并支持我们继续招聘新教师的能力。它不仅将推动由NH资助的各种研究项目和其他研究项目，还将以一种采用可持续设计实践的方式实现这一目标，并确保在我们的动物和其他研究中继续遵守最高标准的护理、安全和行为。

DESCRIPTION (provided by applicant): NYULMC is a leading center of excellence in health care, biomedical research, education, and public service in New York City. Hurricane Sandy resulted in catastrophic damage to NYULMC research infrastructure. As a result, two animal facilities, the Smilow cellar vivarium and the Medical Science Building (MSB) vivarium, and one floor of basic science laboratory space in MSB were rendered unusable for research. The Aims of this application are to restore rodent barrier housing, large animal housing and operating suite, an ABSL-3 facility, and one floor of laboratory space. In addition, at the time of the hurricane, a National Institute of health (NIH) - funded G20 renovation grant (RR-030901) was underway in the MSB vivarium. As the MSB vivarium is no longer usable for animal research, the Aims of this application seek to recover some of the G20 Aims as well. The proposed construction will take place above grade at the ACLS West Tower, adjacent to the NYULMC main campus. NYULMC has a lease from ACLS for 20 years post- occupancy. This replacement of research infrastructure will be able to support investigators with a current annual total of $82,345,944 in active and $118,213,845 in pending research grants. The project outlined in this application is an integral component of our recovery and will restore absolutely critical animal and laboratory facilities current investigators need for their research, and suppor our ability to continue to recruit new faculty. Not only will it propel forward a wide variety of NH-funded and other research projects, it will do so in a way that employs sustainable design practices and ensures continued adherence to the highest standards of care, safety, and conduct in our animal and other research.