Research and Mentoring on Alcohol Clinical and Human Laboratory Research

描述（由申请人提供）：这是Stephen a . Maisto博士的高级科学家研究和指导奖（K05）申请。该申请的主要目标是推进我在以下方面的研究项目：(1)酒精和其他药物评估和治疗研究方法，(2)酒精治疗结果、过程、临床过程和复发，以及(3)人类酒精挑战研究。继续探索纵向研究的统计方法和技术，这些方法和技术可以应用于提高对酒精治疗结果、治疗相关变化机制、酒精治疗临床过程和复发的认识，并增加我在指导初级研究者和博士后研究员方面的成功。我的K05奖的续期将使我能够继续以高水平的活动来追求这些主要目标，这是我目前的K05奖期间的特点，该奖项将于2013年8月31日结束。在K05奖励期间，我建议在上述研究领域继续我的研究计划，该研究计划以锡拉丘兹大学为基础，并与纽约州立大学上州医科大学（纽约州锡拉丘兹）、VA纽约州上州医疗网络和美国其他机构的同事合作。我的导师计划因K05奖而变得可行，包括增加四名新徒弟，三名博士和一名医学博士。正如我从目前的K05奖励开始以来所做的那样，我打算在K05奖励续期期间每年平均保持4名初级研究员和博士后研究员的队列。

DESCRIPTION (provided by applicant): This is a revised competing continuation Senior Scientist Research and Mentorship Award (K05) application for Stephen A. Maisto, Ph.D. The primary goals of this application are to advance my research programs in (1) alcohol and other drug assessment and treatment research methods, (2) alcohol treatment outcomes, process, clinical course, and relapse, and (3) human alcohol challenge research, to continue to explore statistical methods and techniques of longitudinal research that may be applied to advance knowledge about alcohol treatment outcomes, mechanisms of treatment-related change, alcohol treatment clinical course, and relapse, and to add to my success in mentoring junior investigators and postdoctoral ferllows. The renewal of my K05 award would allow me to continue to pursue these primary aims at the high level of activity that has characterized the period of my current K05 award, which ends on 8/31/13. During the K05 award period, I propose to continue my research program in the research areas noted above and that is based in Syracuse University and in collaboration with colleagues at SUNY Upstate Medical University (Syracuse, NY), the VA Medical Upstate NY Network, and at other institutions in the US. My Mentoring Plan made feasible by the K05 award includes the addition of four new mentees, three Ph.D.s and 1 M.D.-Ph.D. As I have done successfully since the beginning of my current K05 award, I intend to maintain a cohort of an average of 4 junior investigator and postdoctoral fellow mentees for each year of the K05 award renewal period.