Persistent, Maladaptive Behaviors: Why We Make Bad Choices

项目摘要/摘要 2016年10月11日至13日，罗切斯特大学神经医学研究所和西尔维奥·O·孔特中心 将举行一次题为“持续的、不适应的行为：为什么我们做出糟糕的选择”的会议。《校长》 调查人员是Conte中心主任Suzanne N.Haber和罗切斯特大学研究所的John Foxe 神经内科主任。组委会成员包括本杰明·格林伯格医学博士、巴特勒医院、 兰迪·巴克纳博士，哈佛大学，刘合生博士，哈佛大学，玛丽·菲利普斯医学博士， 匹兹堡大学，波多黎各大学格雷戈里·奎克博士，史蒂文·拉斯穆森医学博士，布朗 大学。当地组委会成员包括格雷戈里·迪安吉利斯博士、本杰明·海登博士、 布拉德·马洪博士。会议将由相对较短的演讲和充足的讨论时间组成。 该计划旨在让基础和临床科学家参与，特别关注基础 驱动基本行为和行动计划的要素(奖励、恐惧和价值分配)；电路故障 这是具有持续的、习惯性行为的疾病异常的基础，尽管一些人意识到 这些行为是不适应的；疾病中常见的电路部件；计算性 了解这些回路的方法；以及影响这些回路的治疗方法。每个人 会议将以一系列相对较短的重点演讲开始，随后是讨论和咖啡休息。 这为正式和非正式的讨论和互动提供了充足的时间。青年科学家的海报 将在茶歇和用餐时设置在同一个房间，并将在整个会议期间保持开放。AS 正式的演讲很短，我们将要求每个演讲者提交一篇关于他们的主题的评论论文 在会议前发布在我们的网站上。这将使学员有机会回顾背景 会议前的材料。

Project Summary / Abstract On October 11-13, 2016, the University of Rochester Institute of Neuromedicine and the Silvio O. Conte Center will hold a meeting entitled “Persistent, maladaptive behaviors: why we make bad choices”. The Principal Investigators are Suzanne N. Haber, Conte Center Director, and John Foxe, University of Rochester Institute of Neuromedicine, Director. The organizing committee includes, Benjamin Greenberg MD, Butler Hospital, Randy Buckner Ph.D., Harvard University, Hesheng Liu Ph.D., Harvard University, Mary Phillips MD, University of Pittsburgh, Gregory Quirk Ph.D., University of Puerto Rico, and Steven Rasmussen MD, Brown University. The local organizing committee includes Gregory DeAngelis, Ph.D., Benjamin Hayden, and Ph.D., Brad Mahon, Ph.D. The meeting will consist of relatively short talks and ample time for discussion. The program is designed to involve basic and clinical scientists with a specific focus on the fundamental elements that drive basic behaviors and action plans (reward, fear, and value assignment); circuit dysfunctions that underlie abnormalities in diseases with persistent, habit-like behaviors, despite some awareness that these behaviors are maladaptive; the circuit components that are common amongst diseases; computational approaches to understanding these circuits; and therapeutic approaches that effect these circuits. Each session will begin with a series of relatively short focused talks, followed by a discussion and coffee break. This gives ample time for both formal and informal discussions and interactions. Posters by young scientists will be set up in the same room as the coffee breaks and meals and will remain up throughout the meeting. As the formal presentations are short, we will ask each presenter to submit a review paper on their topic that will be posted on our web site prior to the meeting. This will give participants an opportunity to review background material before the meeting.