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中文摘要
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项目摘要 COPACABANA基因组学核心将利用创新的技术提供创新、可靠和透明的服务。 新技术,使项目能够实现其个别和总体目标,并传播新的 由项目开发的工作流程和分析,以更广泛的社区。具体来说,基因组学核心 将使项目1、2和3能够推进验证基因组编辑的质量控制指标 技术,识别用于皮层V层神经元和星形胶质细胞分类的稳健RNA特征 并提供高质量的单细胞RNA-seq数据,并将所有这些分析传播给社区。
英文摘要
Project Summary The COPACABANA Genomics Core will provide innovative, reliable and transparent services using innovative new technologies to enable the Projects to accomplish their individual and overall aims and to disseminate new workflows and assays that are developed by Projects to the wider community. Specifically, the Genomics Core will enable Projects 1, 2 and 3 in advancing the quality control metrics for validating genome-editing technologies, identify robust RNA signatures for classification of cortical layer V neurons and astroglial cells and to provide high-quality single-cell RNA-seq data and disseminate all these analyses to the community.
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STAMP technology to enable single-cell and isoform-sensitive detection of RBP sites
STAMP technology to enable single-cell and isoform-sensitive detection of RBP sites
STAMP technology to enable single-cell and isoform-sensitive detection of RBP sites
Single-Cell Transcriptomic and Epigenetics Core
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