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中文摘要
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技术概要-1 技术组成部分1描述了现有定制软件的基本工作。这 Work将为Xenbase数据库添加新功能,并允许我们同时表示 使用EQ的非洲爪哇实验中的解剖和基因表达表型 语法以及With Go注释。这些目标将通过软件实现 从构建数据库到Xenbase系统的多个级别的开发 对表型的支持一直到用户界面。为了构建它,我们将使用 来自其他MOD的逻辑,如Xenabse使用GMOD/Chado模式,我们将 改编我们已经为gene建立的Web应用程序和接口代码 表情。我们经验丰富的开发团队,以及在此概述的新员工 提案,将在2年内将表型表示法构建到Xenbase中。我们 将添加表型的表示,作为基因表达水平的变化 又是一年。添加内容并与外部资源协作以最大限度地提高 这些数据在理解人类疾病的分子基础方面的影响将需要 另外两年。
英文摘要
Summary Tech-1 Technology Component 1 describes essential work on existing custom software. This work will add new functionality to the Xenbase database and allow us to represent both anatomical and gene expression phenotypes from Xenopus experiments using an EQ syntax as well as with GO annotations. These aims will be achieved though software development at multiple levels of the Xenbase system, from building the database support for phenotypes all the way through to user interfaces. To build this we will use logic from other MODs, that like Xenabse use a GMOD/Chado schema and we will adapt the web-application and interface code that we have already established for gene expression. Our experienced development team, along with the new hires outlined in this proposal, will build phenotype representation into Xenbase in a 2 year time frame. We will add representation of phenotypes as changes in gene expression levels within another year. Adding content and collaborating with external resources to maximize the impact of these data in understanding the molecular basis of human disease will take an additional 2 years.
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Computational Support for All Echinobase Objectives
  • 批准号:
    10715582
  • 项目类别:
  • 资助金额:
    $15.79万
  • 财政年份:
    2023
  • 负责人:
    PETER D VIZE
  • 依托单位:
Software Development to Enhance Echinobase
  • 批准号:
    10715581
  • 项目类别:
  • 资助金额:
    $17.52万
  • 财政年份:
    2023
  • 负责人:
    PETER D VIZE
  • 依托单位:
Computational Support for All Echinobase Objectives
  • 批准号:
    10442597
  • 项目类别:
  • 资助金额:
    $16.77万
  • 财政年份:
    2018
  • 负责人:
    PETER D VIZE
  • 依托单位:
Computational Support for All Echinobase Objectives
  • 批准号:
    10241293
  • 项目类别:
  • 资助金额:
    $15.43万
  • 财政年份:
    2018
  • 负责人:
    PETER D VIZE
  • 依托单位:
海外基金