CSHL 2019 Microbial Pathogenesis and Host Response Conference

微生物致病机理与寄主反应 2019年9月10日至14日 第十二届微生物致病机理和宿主反应国际会议将重点关注 研究传染病的跨学科方法，整合分子微生物学的学科， 真核细胞生物学、免疫学和基因组学。微生物疾病再次成为一种重要的 在世界卫生保健中的中心作用，由于新病原体的出现，共同疾病的重新兴起 病原体和广泛的抗药性。在人类健康之外，毁灭性的大流行正在破坏稳定 生态系统，棕色蝙蝠和两栖动物目前受到极端威胁。这次会议将提供一个内部- 深度关注用来阐明细菌和真菌机制的方法 发病机制，并促进这些概念的应用，以新的策略控制和 传染病的干预。口头和海报会议将集中讨论微生物的主要新兴主题 发病机制和宿主反应，包括：微生物疾病的发病机制和进化； 病原调控，病原体异质性作为适应机制，宿主细胞/病原体 相互作用，以及逃避天然免疫的病原体策略的多样性。会议将整合 细菌和真菌病原体的研究。口头会议将以2-3个由ESTED邀请的讲座开始 该领域的领军人物，随后是从提交的摘要中选择的几个较短的演讲。广泛的主题 个别会议包括：1)病原体共感染；2)感染的细胞生物学；3)病原体的异质性 和疾病结局；4)先天免疫的病原体逃避策略的多样性；5)微生物 进化与毒力；6)胃肠生态学与微生物发病机制。包括两个 海报会议以及在每次演讲后分配充足的提问时间将鼓励 与会者进行了广泛的讨论。会议将足够小(300-400名科学家) 促进这些互动，但规模足够大，不仅允许来自已建立的 调查人员，但也来自初级调查人员和具有新奇视角的人。整合了广泛的 细菌和真菌致病的多种方面与宿主对病原体的反应应促进 在其他关于微生物发病机制的会议上很少实现的新的跨学科相互作用 要么关注范围更窄，要么过于多样化，以至于整合这些主题具有挑战性。由此产生的 跨学科的互动将促进概念和实验方法的发展， 否则可能是不可能的。

Microbial Pathogenesis and Host Response September 10 - 14, 2019 The twelfth international conference on Microbial Pathogenesis and Host Response will focus on interdisciplinary approaches to study infectious disease, integrating the disciplines of molecular microbiology, eukaryotic cell biology, immunology, and genomics. Microbial diseases have once again taken an important central role in health care worldwide, due to the emergence of new pathogens, the re-ascent of common pathogens, and extensive drug resistance. Outside of human health, devastating pandemics are destabilizing ecosystems, with brown bats and amphibians currently under extreme threat. The meeting will provide an in- depth focus on the approaches that are being used to elucidate the mechanisms of bacterial and fungal pathogenesis, and promote the application of these concepts to novel strategies for the control and intervention of infectious diseases. Oral and poster sessions will focus on major emerging themes of microbial pathogenesis and the host response, including: the pathogenesis & evolution of microbial diseases; the regulation of pathogenesis, heterogeneity of pathogens as an adaptive mechanism, host cell/pathogen interactions, and the diversity of pathogen strategies to evade innate immunity. The sessions will integrate studies on bacterial and fungal pathogens. The oral sessions will begin with 2-3 invited talks by established leaders in the field, followed by several shorter talks chosen from submitted abstracts. Broad themes for individual sessions include: 1) pathogen coinfections; 2) cell biology of infections; 3) heterogeneity in pathogen and disease outcomes; 4) the diversity of pathogen evasion strategies of innate immunity; 5) microbial evolution and virulence; and 6) gastrointestinal ecology and microbial pathogenesis. The inclusion of two poster sessions as well as the allotment of ample time for questions following each talk will encourage extensive discussion between the participants. The meeting will be small enough (300 - 400 scientists) to facilitate these interactions, yet large enough to allow for oral presentations not only from established investigators, but also from junior investigators and those with novel perspectives. The integration of a wide variety of aspects of bacterial and fungal pathogenesis with the host response to pathogens should promote new interdisciplinary interactions that are seldom achieved at other meetings on microbial pathogenesis that are either more narrowly focused or so diverse that the topics are challenging to integrate. The resulting interdisciplinary interactions will facilitate the development of conceptual and experimental approaches that might not otherwise be possible.