FDA Vet-LIRN Site Application –AgriLife and the Texas A&M University System

项目摘要 在美国，食源性疾病每年都会导致显著的发病率和死亡率。 沙门氏菌、弯曲杆菌和李斯特菌都能引起人和动物的感染。虽然 人类食源性疾病通常与食用受污染的食物、宠物 可以是细菌病原体的直接和间接来源。美国食品和药物管理局 (FDA)兽医实验室综合反应网络（Vet-LIRN） 实验室合作协议计划旨在促进人类和动物健康 通过提供科学信息和建立实验室能力， 对疾病暴发的调查和对动物饲料问题的调查作出反应， 毒品检测疫情需要能够从地理上不同的地方收集样本 地区得克萨斯州有2500万人口，人口仅次于加州， 马和牛的数量居全国之首因此，重要的是要了解 德克萨斯州内动物和人之间食源性疾病的动态。Texas A&M大学是德克萨斯州唯一的兽医学院。德克萨斯A&M 大学兽医教学医院临床微生物学实验室目前 作为FDA Vet-LIRN实验室实验室的成员帮助开发了Vet- LIRN方法检测沙门氏菌和空肠弯曲菌，参与熟练 作为Vet-LIRN调查的一部分，测试、收集和分析样本。客观 该提案的一个主要目的是在得克萨斯州提供基础设施，以支持样本的收集和测试 支持FDA Vet-LIRN保护人类和动物健康的使命， 及时识别疫情并检测与疫情有关的样本， Vet-LIRN计划办公室需要的监督任务。

PROJECT SUMMARY Foodborne illness causes significant morbidity and mortality each year in the United States. Salmonella, Campylobacter, and Listeria, all cause infections in people and animals. Although human foodborne illness is usually associated with the consumption of contaminated food, pets can be direct and indirect sources of bacterial pathogens. The Food and Drug Administration (FDA) Veterinary Laboratory Integrated Response Network (Vet-LIRN) Veterinary Diagnostic Laboratory Cooperative Agreement Program is designed to promote human and animal health by providing scientific information and building laboratory capacity for routine and emergency response for investigation of outbreaks and to investigate problems with animal feeds and drugs. Detection of outbreaks requires the ability to collect samples from geographically diverse areas. Texas is home to 25 million people, second only to California in human population, and leads the nation in horse and cattle populations. It is therefore important to understand the dynamics of foodborne diseases among animals and people within the State of Texas. Texas A&M University is home to the only College of Veterinary Medicine in Texas. The Texas A&M University Veterinary Medical Teaching Hospital Clinical Microbiology Laboratory currently serves as a FDA Vet-LIRN Laboratory. Members of the laboratory have helped to develop Vet- LIRN methods for detection of Salmonella and Campylobacter jejuni, participated in proficiency testing, and collecting and analyzing samples as part of Vet-LIRN investigations. The objective of this proposal is to provide infrastructure in Texas to support collection and testing of samples from pets to support the FDA Vet-LIRN mission of protecting human and animal health by prompt recognition of outbreaks and testing of samples associated with outbreaks as well as surveillance assignments as needed by the Vet-LIRN Program Office.