Undergraduate Cardiovascular Research Program

摘要 这一新的R25课程旨在吸引本科生参与多学科的翻译 针对心血管疾病的诊断、治疗和预防的心血管研究 (CVD)。代表不足的少数族裔、残疾人和人太少了。 来自农村和市中心，从事心血管疾病研究的人(都得到了NHLBI的认可 工作队审查研究、培训和职业发展方案)。这一计划旨在 让这些背景的学生参与多学科的研究活动，以减轻 心血管疾病。我们为期5年的计划将每年招收12名大二学生参加多年的承诺， 将国家卫生研究院的暑期研究津贴与教育课程相结合 由每个学生在弗吉尼亚州的本科高等学府支持(包括历史上的 少数族裔服务的大学)，以及弗吉尼亚联邦大学(VCU)的研究优势- 包括NIH临床和翻译科学奖和VCU Pauley心脏中心。关键特征 建议的R25计划包括：1)将每个受训者与一名资助的研究导师配对，其 研究重点是心血管疾病；2)优秀的多学科教师，他们是经验丰富的导师；3)获得 来自美国国立卫生研究院资助的主要基础科学、前瞻性队列或 VCU的临床试验通过支持项目的教师；4)由现有的 本科生、研究生和医学院教职员工补充以前没有的心血管疾病研究领域 学生体验；以及5)两个机构研讨会系列，以加强与其他人的互动 来自多个学科的学生和个人。一群来自六(6)个不同种族和性别的教职员工 将参与这一计划的大学已经有过在一年中指导12名学生的经验 前一年成功的、可比的计划。所有教员都有国立卫生研究院或退伍军人事务部校外或其他同行- 审查资金；强有力的机构支持(财政资源、设施和设备)；稳健 与VCU健康差距中心整合，以招募和培训少数族裔个人；以及 支持关键的职业发展活动，如演示文稿、赠款和手稿写作。 这个R25项目的最终目标是吸引和培养一批来自六个国家的优秀年轻学生 (6)弗吉尼亚州的本科院校将熟练掌握心血管疾病的最新发展 多学科转化性研究，谁将为未来在心血管领域的职业生涯做好准备 健康。实现这一目标将增加未得到充分代表的种族/族裔的数量 少数群体、残疾人和来自农村和市中心社区的人成为毕业生 专注于开发多学科翻译研究的新进展的项目 并预防心血管疾病，这是一个主要的公共卫生问题。

Summary This new R25 program is designed to engage undergraduate students in multi-disciplinary translational cardiovascular research directed toward the diagnosis, treatment and prevention of cardiovascular disease (CVD). There are too few under-represented racial/ethnic minorities, individuals with disabilities, and people from rural and inner-city locations who are pursuing careers in CVD research (all recognized by the NHLBI task force review of research training and career development programs). This program is designed to involve students from these backgrounds in multi-disciplinary research activities to reduce the burden of CVD. Our 5-year proposal will enroll 12 sophomore students each year into a multi-year commitment that combines the summer research stipend from this proposed NIH award with an educational curriculum supported by each student’s undergraduate institution of higher learning in Virginia (including historically minority-serving universities), and the research strengths of Virginia Commonwealth University (VCU) – including an NIH Clinical and Translational Science Award and the VCU Pauley Heart Center. Key features of this proposed R25 program include: 1) pairing each trainee with a funded research mentor whose research focuses on CVD; 2) outstanding multidisciplinary faculty who are seasoned mentors; 3) access to multiple phenotypic and biologic materials from major NIH-funded basic science, prospective cohort, or clinical trials at VCU through the supporting program faculty; 4) courses provided by the existing undergraduate, graduate, and medical school faculty to supplement areas of CVD research not previously experienced by students; and 5) two institutional seminar series that enhance interactions with other students and individuals from multiple disciplines. A group of racially and gender diverse faculty from six (6) universities who will be a part of the proposed program already have experience mentoring 12 students in a successful and comparable program in the prior year. All faculty have NIH or VA extramural or other peer- reviewed funding; strong institutional support (financial resources, facilities, and equipment); robust integration with the VCU Center of Health Disparities for recruiting and training minority individuals; and support for key professional development activities such as presentations and grant and manuscript writing. The ultimate goal of this R25 program is to attract and train a cohort of outstanding young students from six (6) undergraduate institutions within Virginia to become fluent in the latest developments of CVD multidisciplinary translational research, who will be well prepared to pursue future careers in cardiovascular health. Accomplishing this goal would augment the number of under-represented racial/ethnic minorities, those with disabilities and persons from rural and inner-city communities into graduate programs focused on developing new advances in multi-disciplinary translational research to treat and prevent cardiovascular disease, a major public health issue.