Administrative Core A

行政核心A项目摘要 行政核心的总体目标是提供行政领导，以支持联合国的使命。 克利夫兰DDRCC。核心支持消化疾病研究人员在凯斯西储大学 （CWRU）和克利夫兰诊所勒纳研究所（CCF LRI）通过1）确保适当分配 克利夫兰DDRCC资源，并为中心提供全面的财务管理，2）继续 以最大限度地提高生产力和效率的方式发展中心，并战略性地发展 克利夫兰DDRCC研究基地在消化道炎症/肿瘤发生和肝脏的主题领域 疾病/代谢，以及3）促进我们中心成员之间的科学合作机会， 我们的初级调查员的发展。中心主任Fabio Cominelli博士和副中心 主任Claudio Fiocchi博士（CCF）和Theresa Pizarro博士（CWRU）提供行政和科学服务， 领导克利夫兰DDRCC。他们的领导能力得到内部顾问的支持， 委员会和执行委员会，由中心主任，核心主任，科学家组成。 项目负责人和两名特别复员方案协调委员会成员。执行委员会每季度举行一次会议， 与中心有关的财务和方案问题。外部咨询委员会由三名 中心各专题领域的国际领导人每年与中心主任和执行主任举行会议， 委员会审查中心并提供关键反馈。中心管理员和行政 助理为复员方案协调中心的日常财务管理和运作提供支助， 顾问定期评估中心的研究基础、核心服务和中心活动， 确保中心继续以具有成本效益的方式满足其成员随着时间的推移不断变化的需求。核心 支持格雷戈里·库珀博士指导的临床元素，该元素提供生物统计/研究设计和 为中心成员提供生物信息学支持服务，以及由Dr. Theresa Pizarro旨在促进消化系统疾病研究的新调查和合作。的 丰富计划支持DDRCC研讨会系列，由中心成员进行研究进展会谈 每年有7名客座教授，参与中西部DDRCC联盟及其年度研究 研讨会（2018年由克利夫兰DDRCC主办），一年两次的克利夫兰IDEAS研讨会， DDRCC青年调查员网络，以及与中心领导和成员的战略规划务虚会。 最后，行政核心协调一个充满活力的试点和可行性方案，由阿米塔布博士指导 促进消化系统疾病初级研究人员的发展。克利夫兰DDRCC 获得了CWRU医学院和CWRU消化健康的特殊机构支持 研究所和CCF LRI和消化系统疾病研究所，并期待着继续其 使命在下一个供资周期。

ADMINISTRATIVE CORE A PROJECT SUMMARY The overall goal of the Administrative Core is to provide administrative leadership to support the mission of the Cleveland DDRCC. The Core supports digestive disease investigators at Case Western Reserve University (CWRU) and the Cleveland Clinic Lerner Research Institute (CCF LRI) by 1) assuring appropriate allocation of Cleveland DDRCC resources and providing overall financial management for the Center, 2) continuing to develop the Center in a manner that maximizes productivity and effectiveness and strategically grows the Cleveland DDRCC Research Base in the thematic areas of Digestive Inflammation/Tumorigenesis and Liver Disease/Metabolism, and 3) fostering opportunities for scientific collaboration among our Center members and development of our junior investigators. The Center Director, Dr. Fabio Cominelli, and Associate Center Directors, Drs. Claudio Fiocchi (CCF) and Theresa Pizarro (CWRU), provide the administrative and scientific leadership for the Cleveland DDRCC. Their leadership is augmented by the support of an Internal Advisory Committee and an Executive Committee, which is composed of the Center directors, Core directors, Scientific Program leaders, and two ad hoc DDRCC members. The Executive Committee meets quarterly to review all financial and programmatic issues related to the Center. An External Advisory Committee composed of three international leaders in the thematic areas of the Center meets annually with the Center Director and Executive Committee to review the Center and provide critical feedback. A Center Administrator and Administrative Assistant provide support for day-to-day financial management and operation of the DDRCC, and a Core Consultant performs regular evaluation of the Center’s Research Base, Core services, and Center activities to assure the Center continues to cost-effectively meet the evolving needs of its members over time. The Core supports a clinical element directed by Dr. Gregory Cooper, which provides biostatical/study design and bioinformatic support services to Center members, as well as a robust Enrichment Program directed by Dr. Theresa Pizarro aimed at fostering new investigations and collaborations in digestive diseases research. The Enrichment Program supports a DDRCC Seminar Series with research-in-progress talks by Center members and seven visiting professors per year, partipation in the Midwest DDRCC Alliance and its annual research symposium (hosted by the Cleveland DDRCC in 2018), the biannual Cleveland IDEAS Symposium, the DDRCC Young Investigators Network, and strategic planning retreats with Center leadership and members. Finally, the Administrative Core coordinates a vibrant Pilot and Feasibility Program directed by Dr. Amitabh Chak to promote the development of junior investigators in digestive diseases. The Cleveland DDRCC has received exceptional institutional support from the CWRU School of Medicine and CWRU Digestive Health Research Institute, and the CCF LRI and Digestive Diseases Instititute and looks forward to continuing with its mission over the next funding cycle.