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联系PD/PI:Reilly,Muredach P NRSA-Training-001(819) J.TL1--培训核心: 项目摘要/摘要 欧文研究所NRSA培训核心的总体目标是将博士后和博士后集中在一起 来自医学、其他健康科学和基础科学的博士生 在哥伦比亚大学(CU),让他们做好准备,成为下一代临床和翻译技术的领导者 调查人员。培训核心由NCATS指定为TL1,建立在典型的NRSA T32培训基础上 程序,但具有独特的创新功能,使其有别于其他T32程序,包括47 at CU.例如,TL1被深度融入我们的整体临床和翻译科学奖(CTSA) 计划中心培训和教育计划,转化(培训和培育研究学者 这就是多学科),它使受训人员能够参与教学和体验计划,包括 专注于团队科学的课程,以及KL2和以患者为导向的硕士学位的学者 研究项目。欧文研究所的TL1在疾病不可知论方法上也不同于典型的T32 招聘和招收实习生,并设计专注于精准医学(PM)。因此, 程序名为TL1-PM。对PM的关注受到了CU范围内PM倡议的刺激基于 第一个资金周期的经验,以及CU项目管理计划的演变,具体目标是 更新是:目标1.进一步发展和完善我们创新的TL1-PM教育和职业发展 计划,从而使我们的学者和受训人员能够利用PM的原则从事跨学科研究 跨所有翻译领域的团队科学,做出新的发现,并准备好实施这些发现 在临床实践和患者利益方面的发现。这款TL1在关注PM方面是创新的,意义重大 课程作业和研讨会,有组织的职业发展课程,并要求所有受训人员参加 外星人。在接下来的五年里,将增加新的机会,包括一些专注于团队和 实施科学。不太成功的项目将被缩减或终止。目标2.展示 通过对质量的持续监测和评估,确保现有和新项目的有效性 改进,使用NCATS通用指标以及我们本地的定制指标来评估 我们的教育项目涉及研究成果和毕业生的职业发展轨迹。目标3.加速 传播新的教育提供方法、评估受训人员的新方法的结果 向我们在CU的合作伙伴介绍增强跨学科团队科学技能的学习和最佳实践 CTSA中心(Tricon)和CTSA计划网络遍布全国。 项目摘要/摘要页1312 联系PD/PI:Reilly,Muredach P NRSA-Training-001(819) J.NSRA培训核心:参考资料 1. &/、&&HQWHU IRU/HDGLQJ、QQRYDWLRQ&ROODERUDWLRQ?&RUH FRPSHWHQFLHV IRU FOLQLFDO DQG WUDQVODWLRQDO UHVHDUFK?>$Sulo@? KWWSV Folf- FWVD规则VLWHV GHIDXOW ILOHV&76$B&RUHB&RPSHWHQFLHVBILQDOB SGF - $EHGLQ=5HEHOOR 7-5LFKDUGV%)3LQFXV+$0HQWRU WUDLQLQJ ZLWKLQ DFDGHPLF KHDOWK FHQWHUV ZLWK&OLQLFDO DQG 7UDQVODWLRQDO 6FLHQFH$ZDUGV临床翻译科学。-30&,‘30&。 7LOOPDQ 5(-DQJ 6$EHGLQ=5LFKDUGV%)6SDHWK-5XEOHH%3LQFXV+$3ROLFLHV DFWLYLWLHV DQG VWUXFWXUHV VXSSRUWLQJ UHVHDUFK PHQWRULQJ D QDWLRQDO VXUYH\RI DFDGHPLF KHDOWK FHQWHUV ZLWK FOLQLFDO DQG 学术医学:美国医学院协会杂志。 -DOI$&0 E H E 30&. $EHGLn?=%LVNXS(6LOHt.*DUEXWW-0.URHQNH。HOGPDQ 0‘0F*HH 5-U)OHPLQJ 0?3LQFXV+$.‘HULYLQJ FRPSHWHQFLHV IRU PHQWRUV RI FOLQLFDO DQG WUDQVODWLRQDO VFKRODUV.CLIN Transl Sci. -XQ-。30&,‘30&。 (IVWDWKLRX-$‘UXPP 05 3DO 3/DZWRQ’0 2 1HLOO 50 1LHPLHUNo$/HIIHUW/5/RHIIOHU-6 6KLK+$ Long-Whup LPSDFW RI D IDFXOW\PHQWRULQJ SURJUDP LQ DFDGHPLF PHGLFLQH PLoS One.1 RY 1e DOI MRXUQDO SRQH 30&,‘30&. )DundV$+%RQLIDFLQo(7XUQHU 5 7LOVWUa 6$&RUEHOOL-$0HQWRUVKLS RI:RPHQ LQ$FDGHPLF 0HGLFLQH a 6\VWHPDWLF 5HYLHZ J代实习生MED-XO-DOI V 30&,‘30&。 ‘DUE\VKLUH’*RUGRQ 0%DNHU 3$JLXV 6 0F$OHHU 6 6\VWHPDWLF UHYLHZ RI LQWHUYHQWLRQV WR HQFRXUDJH 医学教师??-‘2; 30,‘ .H\VHU‘-$EHGLQ=6FKXOW]’-3LQFXV+$0HQWRUVKLS LQ wkh FRQWH[W RI LQWHUGLVFLSOLQDU\JHULDWULF UHVHDUFK OHVVRQV OHDUQHG IURP WKH 5$1‘+DUWIRUG 3URJUDP IRU%XLOGLQJ,QWHUGLVFLSOLQDU\*HULDWULF 5HVHDUFK&HQWHUV美国老年医学学会杂志。-。30,‘1 .H\VHU‘-/DNRVNL-0/DUD-&LQLVRPR 6 6FKXOW]’-:LOOLDPV 9/=HOOHUV‘)3LQFXV+$$GYDQFLQJ LQVWLWXWLRQDO HIIRUWV WR VXSSRUW UHVHDUFK PHQWRUVKLS D FRQFHSWXDO IUDPHZRUN DQG VHOI-DVVHVVPHQW WRRO $FDGHPLF PHGLFLQH美国医学院协会期刊-30,‘ 。 参考文献1313页
英文摘要
Contact PD/PI: Reilly, Muredach P NRSA-Training-001 (819) J. TL1 – TRAINING CORE: PROJECT SUMMARY/ABSTRACT The overarching goal of the Irving Institute's NRSA Training Core is to bring together pre-doctoral and post- doctoral trainees from across the broad spectrum of medicine, the other health sciences, and the basic sciences at Columbia University (CU), and prepare them to be leaders of the next generation of clinical and translational investigators. The Training Core, designated as a TL1 by NCATS, is founded upon a typical NRSA T32 training program, but has unique and innovative features distinguishing it from other T32 programs including the 47 at CU. For example, the TL1 is deeply integrated into our overall Clinical and Translational Science Award (CTSA) Program hub training and education program, TRANSFORM (Training And Nurturing Scholars For Research that is Multidisciplinary), which enables trainees to participate in didactic and experiential programs, including programs focused on team-science, alongside scholars in the KL2 and Master's Degree in Patient Oriented Research programs. The Irving Institute's TL1 also differs from a typical T32 in its disease agnostic approach to recruitment and enrollment of trainees, and the designed focus on Precision Medicine (PM). As such, the program is named TL1-PM. The focus on PM has been stimulated by the CU-wide initiative in PM. Based on experiences during the first funding cycle, as well as the evolution of PM programs at CU, the Specific Aims for the renewal are: Aim 1. To further develop and refine our innovative TL1-PM education and career development program, thereby empowering our scholars and trainees to use the principles of PM to engage in interdisciplinary team science across all translational domains, make new discoveries, and be equipped to implement those discoveries into clinical practice and patient benefit. This TL1 is innovative in its focus on PM, significant coursework and seminars, a structured career development curriculum, and requiring all trainees to take externships. In the next five years, new opportunities will be added, including some focused on team and implementation science. Less successful programs will be scaled back or ended. Aim 2. To demonstrate the effectiveness of existing and new programs through continuous monitoring and assessment for quality improvement, using NCATS Common Metrics as well as our local, customized metrics to evaluate the impact of our educational programs on research output and the career trajectories of our graduates. Aim 3. To accelerate dissemination of the results of novel educational delivery approaches, new methods for assessing trainee learning, and best practices for enhancing interdisciplinary team science skills, to our partners at CU, regional CTSA Hubs (TriCon), and CTSA Program network throughout the nation. Project Summary/Abstract Page 1312 Contact PD/PI: Reilly, Muredach P NRSA-Training-001 (819) J. NSRA TRAINING CORE: REFERENCES 1. &/,& &HQWHU IRU /HDGLQJ ,QQRYDWLRQ &ROODERUDWLRQ ?&RUH FRPSHWHQFLHV IRU FOLQLFDO DQG WUDQVODWLRQDO UHVHDUFK ? >$SULO @ ? KWWSV FOLF- FWVD RUJ VLWHV GHIDXOW ILOHV &76$B&RUHB&RPSHWHQFLHVBILQDOB SGf - $EHGLQ = 5HEHOOR 7- 5LFKDUGV %) 3LQFXV +$ 0HQWRU WUDLQLQJ ZLWKLQ DFDGHPLF KHDOWK FHQWHUV ZLWK &OLQLFDO DQG 7UDQVODWLRQDO 6FLHQFH $ZDUGV Clin Transl Sci. - 30&,' 30& . 7LOOPDQ 5( -DQJ 6 $EHGLQ = 5LFKDUGV %) 6SDHWK-5XEOHH % 3LQFXV +$ 3ROLFLHV DFWLYLWLHV DQG VWUXFWXUHV VXSSRUWLQJ UHVHDUFK PHQWRULQJ D QDWLRQDO VXUYH\ RI DFDGHPLF KHDOWK FHQWHUV ZLWK FOLQLFDO DQG WUDQVODWLRQDO VFLHQFH DZDUGV Academic medicine: journal of the Association of American Medical Colleges. - doi $&0 E H E 30& . $EHGLn?= %LVNXS ( 6LOHt . *DUEXWW -0 .URHQNH . )HOGPDQ 0' 0F*HH 5 -U )OHPLQJ 0 ?3LQFXV+$.'HULYLQJ FRPSHWHQFLHV IRU PHQWRUV RI FOLQLFDO DQG WUDQVODWLRQDO VFKRODUV. Clin Transl Sci. -XQ - . 30&,' 30& . (IVWDWKLRX -$ 'UXPP 05 3DO\ -3 /DZWRQ '0 2 1HLOO 50 1LHPLHUNo $ /HIIHUW /5 /RHIIOHU -6 6KLK +$ Long-WHUP LPSDFW RI D IDFXOW\ PHQWRULQJ SURJUDP LQ DFDGHPLF PHGLFLQH PLoS One. 1RY 1 e doi MRXUQDO SRQH 30&,' 30& . )DUNDV $+ %RQLIDFLQo ( 7XUQHU 5 7LOVWUa 6$ &RUEHOOL -$ 0HQWRUVKLS RI :RPHQ LQ $FDGHPLF 0HGLFLQH a 6\VWHPDWLF 5HYLHZ J Gen Intern Med -XO - doi V - - - 30&,' 30& . 'DUE\VKLUH ' *RUGRQ 0 %DNHU 3 $JLXV 6 0F$OHHU 6 6\VWHPDWLF UHYLHZ RI LQWHUYHQWLRQV WR HQFRXUDJH FDUHHUV LQ DFDGHPLF PHGLFLQH Medical Teacher.? ? - '2, ; 30,' .H\VHU '- $EHGLQ = 6FKXOW] '- 3LQFXV +$ 0HQWRUVKLS LQ WKH FRQWH[W RI LQWHUGLVFLSOLQDU\ JHULDWULF UHVHDUFK OHVVRQV OHDUQHG IURP WKH 5$1' +DUWIRUG 3URJUDP IRU %XLOGLQJ ,QWHUGLVFLSOLQDU\ *HULDWULF 5HVHDUFK &HQWHUV Journal of the American Geriatrics Society. - . 30,' 1 .H\VHU '- /DNRVNL -0 /DUD-&LQLVRPR 6 6FKXOW] '- :LOOLDPV 9/ =HOOHUV ') 3LQFXV +$ $GYDQFLQJ LQVWLWXWLRQDO HIIRUWV WR VXSSRUW UHVHDUFK PHQWRUVKLS D FRQFHSWXDO IUDPHZRUN DQG VHOI-DVVHVVPHQW WRRO $FDGHPLF PHGLFLQH Journal of the Association of American Medical Colleges - 30,' . References Cited Page 1313
期刊论文(58)
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会议论文
DOI: 10.1177/1758834018757175
发表时间: 2018
期刊: Therapeutic advances in medical oncology
影响因子: 4.9
作者: [Yang J, Manson DK, Marr BP, Carvajal RD]
通讯作者: Carvajal RD
DOI: 10.1371/journal.pone.0271884
发表时间: 2022
期刊: PLOS ONE
影响因子: 3.7
作者: [Topaz, Maxim, Zolnoori, Maryam, Norful, Allison A., Perrier, Alexis, Kostic, Zoran, George, Maureen]
通讯作者: George, Maureen
DOI: 10.1101/gad.317966.118
发表时间: 2018-09-01
期刊: Genes & development
影响因子: 10.5
作者: [Smith MJ, Bryant EE, Rothstein R]
通讯作者: Rothstein R
The gut microbiome, short chain fatty acids, and related metabolites in cystic fibrosis patients with and without colonic adenomas.
患有和不患有结肠腺瘤的囊性纤维化患者的肠道微生物组、短链脂肪酸和相关代谢物。
DOI: 10.1016/j.jcf.2023.01.013
发表时间: 2023
期刊: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
影响因子: --
作者: [Baldwin-Hunter,BrittanyL, Rozenberg,FelixD, Annavajhala,MediniK, Park,Heekuk, DiMango,EmilyA, Keating,ClaireL, Uhlemann,Anne-Catrin, Abrams,JulianA]
通讯作者: Abrams,JulianA
共 36 条
    Midcareer investigator award in patient-oriented research in the area of perinatal-developmental neuroscience
    Midcareer investigator award in patient-oriented research in the area of perinatal-developmental neuroscience
    Midcareer investigator award in patient-oriented research in the area of perinatal-developmental neuroscience
    Maternal Immune Activation and Fetal-Infant Neurobehavioral Development
    海外基金