Enhancing dissemination and career development in sex and gender translational science in alcohol use

项目摘要 在过去的十年里，女性的酒精使用量大幅增加，与 男性的增长幅度较小。虽然饮酒在两性中都与重大的健康风险密切相关， 与男性相比，女性加剧了与酒精相关的健康后果。使这一点复杂化 问题，酒精使用的治疗发展没有考虑，也没有对已知的性别差异做出反应 酗酒。出于这些原因，该领域需要更多的能力来进行翻译科学 研究性别和性别差异与饮酒的关系。这份R13提案是一份申请资金的BI- 一年一度(每两年一次)，为期一天的卫星会议在酒精问题研究会所在地举行 会议的重点是性别翻译创新和酒精使用的性别差异。这次会议 将起到几个关键作用：1)作为国际科学家、临床医生和 受训人员支持思想交流和促进性/性别和饮酒方面的新合作 跨越T1到T4转换。2)促进下一代转化醇的发展 研究人员，通过向研究生、博士后研究员和初学者提供25项旅行奖励 来展示他们的研究成果。3)提供关于最佳做法程序和定义的信息 与性/性别和酒精研究有关的参数。互动节目将以两位领军人物为特色 国际演讲者和受训人员，最大限度地实现多样性和包容性。这项拟议的R13赠款将提供 为NIAAA的使命做出了独特的贡献，即将性和性别“纳入设计、分析和科学 报告其资助的研究。这是确保每个人，无论性别或性别， 性别，从酒精研究中获益“32.

Project Abstract Alcohol use among women has substantially and concerningly increased over the last decade, relative to smaller increases among men. While drinking is strongly associated with significant health risks in both sexes, females have exacerbated alcohol-related health consequences when compared to males. Compounding this issue, treatment development for alcohol use has not considered, nor is responsive to known sex differences in alcohol use. For these reasons, the field requires an increased capacity to conduct translational science to study sex and gender differences in relation to alcohol use. This R13 proposal is a request for funding for a bi- annual (once every two years), one-day satellite meeting held at the site of the Research Society on Alcohol conference to focus on translational innovations in sex and gender differences in alcohol use. This meeting would serve several key functions: 1) To serve as a hub for an international group of scientists, clinicians, and trainees to support the exchange of ideas and promote new collaborations on sex/gender and alcohol use spanning T1 to T4 translation. 2) To foster the development of the next generation of translational alcohol researchers, by supporting 25 travel awards to graduate students, postdoctoral fellows, and early-career junior faculty to present their research. 3) To provide information on best practice procedures and definitional parameters relevant to the study of sex/gender and alcohol. An interactive program would feature both leading international speakers and trainees, maximizing diversity and inclusion. This proposed R13 grant will provide a unique contribution to NIAAA’s mission to incorporate sex and gender “into the design, analysis, and scientific reporting of the studies it funds. This is a critical step toward ensuring that everyone, regardless of sex or gender, benefits from alcohol research advances”32.