ACCESS: Accelerating Cervical Cancer Elimination through the integration of Screen-and-treat Services

项目总结 我的提案是对被确认为NOT-CA-23-038的特殊利益通知(NOSI)的回应。 我是医学社会学和人类学的助理教授，也是 尼日利亚恩苏卡大学翻译与实施科学(CTAIR)。我的研究重点是 中低收入国家的姑息治疗(PC)、癌症和妇女健康。这 行政辅导员奖将为我提供所需的支持，以实现以下3个关键 LMIC背景下研究的职业发展目标：(1)提高我在社区的技能 参与性研究、利益相关者的参与和项目整合，特别是在PC临床环境中；(2) 深入了解实施框架和方法，以帮助缩小 实施科学和实施实践；(3)获得个人电脑研究方面的技能和内容专长。我 我会和我的导师一起进行研究和工作，至少有40%的时间在尼日利亚 实施科学联盟-模型创新和研究中心(NISA-MIRC)，一个以实践为基础的 研究网络覆盖尼日利亚的六个地理区域。为了实现这些目标，我已经把 共同组成的辅导团队包括：(1)来自加州大学的美国小学导师格雷戈里·亚伦斯教授， 圣地亚哥，实施科学专家；(2)LMIC的主要导师，Echezona Ezeanolue教授 来自尼日利亚大学，是基于社区的参与性研究和临床研究方面的专家； (3)LMIC联合导师，尼日利亚大学教学医院[UNTH]的专家托尼娅·奥尼卡博士 从事PC研究和实践；(4)LMIC同行导师，来自翻译中心的John Olawepo博士和 实施研究[CTAIR]，他是卫生系统集成方面的专家。我的导师团队将 支持我的能力建设和研究项目，其中包括探索可行性和 文化适应和综合个人电脑套餐的可接受性，以促进艾滋病毒携带者妇女的福祉 (WLHIV)和宫颈癌。我的具体目标是：(1)共同创建和开发可行的、适应文化的、 以及来自NISA-MIRCs的WLHIV和宫颈癌的可持续PC服务包。我们将调整核心 国家综合癌症网络(NCCN)指南中推荐的PC服务元素使用 成熟的混合方法方法；以及(2)试行适应的多组分PC包以确定 两个NISA-MIRC设施的可行性和可接受性。在这一年的行政奖励，我的尼日利亚- 美国的导师、共同导师和同伴导师将在各自的领域提供额外的培训和指导 专业知识，包括实施科学、基于社区的参与性研究、个人计算机和卫生系统 整合。

PROJECT SUMMARY My proposal is a submission in response to the Notice of Special Interest (NOSI) identified as NOT-CA-23-038. I am an Assistant Professor of Medical Sociology and Anthropology and a Research Fellow at the Center for Translation and Implementation Science (CTAIR) at the University of Nigeria, Nsukka. My research focuses on palliative care (PC), cancer and women’s health in low- and middle-income countries (LMICs). This administrative supplement mentor award will provide me with the support needed to achieve the following 3 key career development objectives for research in LMIC settings: (1) Sharpen my skills in community based participatory research, stakeholder’s engagement and program integration especially in PC clinical settings; (2) Acquire in-depth knowledge of implementation frameworks and methods to help close the gap between implementation science and implementation practice; (3) Acquire skills and content expertise in PC research. I will conduct research and work with my mentors for a minimum of 40% of my time within the Nigerian Implementation Science Alliance-Model Innovation and Research Centers (NISA-MIRCs), a practice-based research network across the six geographical regions in Nigeria. To accomplish these objectives, I have put together a mentoring team including: (1) a US Primary Mentor, Prof. Gregory Aarons from University of California, San Diego who is an expert in Implementation Science; (2) a LMIC Primary Mentor, Prof. Echezona Ezeanolue from the University of Nigeria, who is an expert in community-based participatory research and clinical research; (3) a LMIC Co-Mentor, Dr Tonia Onyeka from University of Nigeria Teaching Hospital [UNTH], who is an expert in PC research and practice; (4) a LMIC Peer-Mentor, Dr John Olawepo from Center of Translation and Implementation Research [CTAIR], who is an expert in health systems integration. My team of mentors will support my capacity building and research project, which includes a pilot study to explore the feasibility and acceptability of a culturally adapted and integrated PC package to promote wellbeing of women living with HIV (WLHIV) and cervical cancers. My specific aims are to: (1) Co-create and develop feasible, culturally adapted, and sustainable PC service package with WLHIV and cervical cancer from the NISA-MIRCs. We will adapt core elements of PC services recommended in the National Comprehensive Cancer Network (NCCN) guideline using well-established mixed method approaches; and (2) Pilot the adapted multicomponent PC package to determine feasibility and acceptability at two NISA-MIRCs facilities. During the year of this administrative award, my Nigeria- and US-based mentors, co-mentor, and peer-mentor will provide additional training and guidance in their areas of expertise including implementation science, community based participatory research, PC, and health systems integration.