UNC Center for AIDS Research Core F Biostatistics

项目总结/摘要-生物统计学核心（核心F） 生物统计学核心的全面、长期目标是提供最先进的统计数据， 支持非洲艾滋病毒/艾滋病研究中心的艾滋病毒/艾滋病相关研究。具体目标包括：（1）提供广泛的 一系列合作生物统计服务;（2）开发、实施和传播创新的 艾滋病研究的统计方法;（3）促进CFAR内部的研究，促进CFAR之间的合作， 支持NIH HIV研究网络和国际HIV研究;（4）支持科学工作 小组（SWG）和研究兴趣小组（RIG），培训和指导;（5）进行战略规划， 评价和传播/外联。为了实现这些目标，生物统计学核心的成员积极主动地 与CACFAR调查人员合作，确定并提供高效设计所必需的服务， 开展、分析和出版艾滋病毒研究。核心有助于构建假设， 研究设计的开发，资助申请的准备，适当的统计方法的选择，以及 提供统计分析。发展奖获得者、早期研究者和经验丰富的 新的艾滋病毒研究人员获得核心服务的最高优先权。核心也在发展， 根据CFAR研究的需要，采用创新的统计方法。此外，核心还提供 培训和教育CFAR研究社区，使调查人员具备传统的以及 开展艾滋病毒相关研究所需的创新统计方法。来自联合国的强有力的机构支持 生物统计部使核心能够充分利用现有的基础设施，资源和 与在统计学专业领域享有盛誉的教师保持联系。领导和战略 核心计划的规划将通过与CFAR执行委员会的磋商、CFAR调查 成员，内部咨询委员会，外部咨询委员会，并通过参与CFAR 撤退。

PROJECT SUMMARY/ABSTRACT – BIOSTATISTICS CORE (CORE F) The comprehensive, long-term objectives of the Biostatistics Core are to provide state-of-the-art statistical support for HIV/AIDS-related research of the UNC CFAR. The specific aims include: (1) providing a broad spectrum of collaborative biostatistical services; (2) developing, implementing, and disseminating innovative statistical methods for HIV research; (3) facilitating intra-CFAR research, fostering inter-CFAR collaborations, and supporting NIH HIV research networks and international HIV research; (4) supporting Scientific Working Groups (SWG) and Research Interest Groups (RIG), training, and mentoring; (5) conducting strategic planning, evaluation, and dissemination/outreach. To achieve these aims, members of the Biostatistics Core proactively engage with UNC CFAR investigators to identify and deliver services essential for highly productive design, conduct, analysis and publication of HIV research. The Core contributes to the framing of hypotheses, development of study designs, preparation of grant applications, selection of appropriate statistical methods, and delivery of statistical analyses. Developmental Awardees, Early Stage Investigators, and experienced investigators new to HIV research receive highest priority for Core services. The Core also develops and implements innovative statistical methodologies as needed for CFAR studies. Additionally, the Core provides training and education to the CFAR research community to equip investigators with traditional as well as innovative statistical methods needed to conduct HIV related research. Strong institutional support from the UNC Department of Biostatistics allows the Core to take full advantage of existing infrastructure, resources and contacts with faculty renowned for their expertise in specialized fields of statistics. Leadership and strategic planning of the Core will be guided by consultation with the CFAR Executive Committee, surveys of the CFAR membership, an Internal Advisory Board, an External Advisory Board, and through participation in CFAR retreats.