Louisiana Clinical and Translational Science Center - N3C supplement

项目摘要/摘要 路易斯安那州临床和转化科学(LA CATS)中心是由主要学术机构 以及路易斯安那州的生物医学研究中心。彭宁顿生物医学研究中心是 领导机构，并将继续与路易斯安那州立大学健康(LSUH)-新奥尔良合作 杜兰大学健康科学中心参与了这一倡议。路易斯安那州立大学什里夫波特，路易斯安那州立大学(指挥棒 Rouge)、泽维尔大学和新奥尔良儿童医院是第一周期的早期研究伙伴。 路易斯安那州东南部退伍军人医疗系统，纽约新成立的大学医疗中心 奥尔良(10亿美元的国家投资)、Ochsner Health和LSUH-no牙科学校在 周期2.洛杉矶CATS中心正在为路易斯安那州发展一个统一的临床转化科学项目 基于创建协同计划和来自所有主要行业的无与伦比的协作 该州的学术和生物医学研究机构。自9年前成立以来，洛杉矶猫队 中心拥有：1)成功利用多个参与机构的资源和专业知识 建立充满活力的全州研究基础设施；2)发展高度协同和一体化 合作计划；3)在所有机构实施系统的临床研究方法， 这包括新的智能IRB Reliance Model审查；以及4)实施了高效的 建立在合作伙伴之间前所未有的信任基础上的治理体系。洛杉矶猫正在经历 通过关键指标评估的研究效率的指数级增长，包括 外部赠款奖，作者承认LA的出版物增加了两倍多 CATS中心的资源和服务，600多名研究人员从我们的服务中受益并使用我们的服务。 值得注意的是，在一个以来自COVID的独特和前所未有的挑战为标志的时期 然后飓风艾达，洛杉矶猫已经实现了，并在许多情况下超过了它所宣布的目标和 预计的里程碑。事实上，自2020年3月COVID大流行袭击路易斯安那州以来，洛杉矶猫科动物一直领先 多次成功申请行政副刊和国家创新系统奖，特别是 通过RADx-UP促进服务不足的黑人社区的COVID检测和疫苗接种 计划，以及最近我们与Idea State iScore财团在国家 长期冠状病毒倡议-SARS-CoV-2感染的急性后遗症(PASC)/RECOVER试验。然而，我们 充分认识到我们的工作才刚刚开始，因为我们集体解决差距和改善 我们公民的生命。同样明显的是，我们正在缓慢但肯定地影响公共卫生 一次一个项目！随着新服务的提出和额外资源的增加，我们的 中心处于独特的地位，可以将我们的活动和资源投入到我们未来5年的主要主题中- 年周期，将“解决健康差距和改善我们公民的健康结果” “服务”

Project Summary/Abstract The Louisiana Clinical and Translational Science (LA CaTS) Center is a consortium of the major academic and biomedical research centers in the State of Louisiana. Pennington Biomedical Research Center is the lead institution and will continue to partner with Louisiana State University Health (LSUH)-New Orleans and Tulane University Health Sciences Center in this initiative. LSUH-Shreveport, LSU-A&M (Baton Rouge), Xavier University and Children's Hospital New Orleans, were early Research Partners in cycle 1. Southeast Louisiana Veterans Healthcare System, a newly opened University Medical Center in New Orleans ($1 billion State investment), Ochsner Health and the LSUH-NO School of Dentistry joined during cycle 2. The LA CaTS Center is growing a unified clinical translational science program for Louisiana based on the creation of synergistic programs and unparalleled collaboration from all the major academic and biomedical research institutions in the state. Since inception 9 years ago, the LA CaTS Center has: 1) successfully leveraged resources and expertise of multiple participating institutions to build a vibrant statewide research infrastructure; 2) developed highly synergistic and integrative collaborative programs; 3) implemented a systematic approach to clinical research across all institutions, that includes a new SMART IRB Reliance Model review; and 4) implemented a highly effective governance system based on an unprecedented level of trust between partners. LA CaTS is experiencing exponential growth in research productivity as assessed by key metrics including a three-fold increase in external grant awards, a more than two-fold increase in publications with authors acknowledging LA CaTS Center resources and services and over 600 researchers benefiting from and using our services. Notably, during a period that has been marked by unique and unprecedented challenges from COVID and then Hurricane Ida, LA CaTS has achieved, and in many cases exceeded, its stated objectives and projected milestones. Indeed, since the COVID pandemic hit Louisiana in March of 2020, LA CaTS has led multiple successful grant applications for Administrative Supplements and NOSI awards, notably to facilitate COVID testing and vaccinations in underserved Black communities through the RADx-UP program and most recently our partnership with the IDeA state ISCORE consortium on the national Long-COVID initiative - Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)/RECOVER trial. However, we fully recognize that our work has only just begun, as we collectively address disparities and improve the lives of our citizens. It is also apparent, that slowly, but surely, we are impacting public health one project at a time! With new services proposed and the additional resources that will be added, our Center is uniquely positioned to devote our activities and resources to our major theme for the next 5- year cycle that will “address health disparities and improve the health outcomes of the citizens we serve”