Southern California Center for Chronic Health Disparities in Latino Children and Families.

项目摘要/摘要 在美国拉丁裔成年人中，糖尿病前期和2型糖尿病(T2D)的患病率是 严重的健康问题。T2D影响了大约15%的拉丁裔，约占1000万 在个人方面，与非西班牙裔白人相比，存在明显的差距。这一创新的总体目标是 干预项目是为了加强糖尿病前期患者的血糖控制，防止病情恶化 到拉丁裔中的T2D。该项目旨在开发和评估一种新的干预措施，名为Mi Control！，它 将连续血糖监测(CGM)反馈与最新的无创自我监测相结合 技术与T2D预防教育视频剪辑。这项干预措施将专门针对 拉美人，基于从西班牙语和/或英语的经历和反馈中收集的信息- 会说拉丁语的社区卫生工作者(Promotores)戴着CGM设备。该项目由三个部分组成 实现其目标的迭代研究：研究1：这项干预发展研究将涉及20 Promotores de salud，他将佩戴CGM传感器14天。该传感器将提供实时智能手机 对血糖变异性的视觉和音频反馈，参与者将保持有时间戳的饮食记录。 将进行视频采访，以捕捉体验叙事并探索其好处， 障碍，以及与CGM设备相关的行为变化。将从这些视频剪辑中选择和编辑视频剪辑 采访为干预创建了一系列基于智能手机的教育剪辑。一种人工智能 将使用(AI)工具进行语言翻译。研究2：这项可行性研究旨在评估小米的影响 控制住！关于血糖数据获取和结果的一项独立样本的30个促进剂 糖尿病前期。参与者将佩戴CGM设备14天，研究将包括一个控制期 随后是一段时间，CGM血糖水平反馈和智能手机文本链接到小米控制！ 视频剪辑。将收集对CGM设备和干预的满意度测量。这项研究将 评估小米控制的可行性！语言翻译的人工智能工具的增强，及其对 确诊为糖尿病前期的拉丁裔促进者的血糖控制和知识保留。研究3： 这项概括性研究旨在评估小米控制的有效性！论血糖控制与饮食行为 在40名确诊为糖尿病前期的拉丁裔父母的社区样本中。参与者将是 从正在进行的拉丁裔家庭队列研究中招募的儿童的父母(中心项目1)。参与者将 体验与研究2相同的研究方法和蒙面期间的血糖控制和饮食行为 和未屏蔽的相位将进行比较。总体而言，该项目将有助于开发一个 创新的干预措施，以改善糖尿病前期血糖控制和预防拉丁裔人群的T2D。通过 利用CGM和人工智能等新兴技术，并针对特定需求进行干预 对于拉丁美洲人，这项研究旨在解决在这一人群中观察到的显著健康差距。

Project Summary/Abstract The prevalence of prediabetes and type 2 diabetes (T2D) among Latino adults in the United States is a significant health concern. With T2D affecting approximately 15% of Latinos, accounting for about 10 million individuals, there is a clear disparity compared to non-Hispanic Whites. The overarching goal of this innovative intervention project is to enhance glycemic control in individuals with prediabetes and prevent the progression to T2D among Latinos. This project aims to develop and evaluate a new intervention, called Mi Control!, which combines continuous glucose monitoring (CGM) feedback using the latest non-invasive self-monitoring technology with T2D prevention educational video clips. The intervention will specifically target the needs of Latinos, based on information gathered from the experiences and feedback of Spanish- and/or English- speaking Latino community health workers (Promotores) wearing CGM devices. The project consists of three iterative studies to achieve its objectives: Study 1: This intervention development study will involve 20 Promotores de salud, who will wear a CGM sensor for 14 days. The sensor will provide real-time smartphone visual and audio feedback on glycemic variability, and participants will maintain timestamped dietary records. Video-recorded interviews will be conducted to capture the experiential narrative and explore the benefits, barriers, and behavior changes related to the CGM device. Video clips will be selected and edited from these interviews to create a series of smartphone-based educational clips for the intervention. An artificial intelligence (AI) tool will be utilized for language translation. Study 2: This feasibility study aims to assess the impact of Mi Control! on glycemic data capture and outcomes among an independent sample of 30 Promotores with prediabetes. Participants will wear the CGM device for 14 days, and the study will include a control period followed by a period with unmasked CGM glycemic feedback and smartphone text links to the Mi Control! video clips. Measures of satisfaction with the CGM device and the intervention will be collected. The study will evaluate the feasibility of Mi Control! augmented by the AI tool for language translation, and its impact on glycemic control and knowledge retention among the Latino Promotores with confirmed prediabetes. Study 3: This generality study aims to assess the effectiveness of Mi Control! on glycemic control and dietary behavior among a community-based sample of 40 Latino parents with confirmed prediabetes. Participants will be parents of children recruited from an ongoing cohort study of Latino families (Center Project 1). Participants will experience the same study method as in Study 2 and glycemic control and dietary behavior during the masked and unmasked phases will be compared. Overall, this project will contribute to the development of an innovative intervention to improve prediabetes glycemic control and prevent T2D in the Latino population. By utilizing emerging technologies, such as CGM and AI, and tailoring the intervention to the specific needs of Latinos, this research aims to address the significant health disparities observed in this population.