Mechanisms of central nervous system disease induced by dysregulated interferon signalling

干扰素是一种蛋白质，一方面可以保护细胞免受病毒等感染因子的侵害，但另一方面也会导致大脑损伤和疾病。在这个项目中，干扰素影响大脑产生这些结果的方式将被研究。这项工作的结果将促进我们对干扰素如何发挥作用的理解，并可能为对抗神经系统的免疫和感染性疾病提供更好的方法。

Interferons are proteins that on one hand have been found to protect cells against infectious agents such as viruses but on the other can cause injury and disease in the brain. In this project the way in which interferons affect the brain to bring about these outcomes will be studied. The results of this work will advance our understanding of how interferons function and may lead to better approaches for combating immune and infectious diseases of the nervous system.