Michigan Alzheimer's Disease Research Center-Supplement

摘要 ADRD中的健康差距仍然是一个主要的社会和健康正义挑战， 美国的弱势群体。事实上，黑人/非洲裔美国人和拉丁美洲人更有可能不 接受痴呆症诊断并在就医时受到歧视表明， ADRD可能大于估计值。密歇根阿尔茨海默病研究中心（Michigan ADRC） 于2021年9月退还，作为一个三所大学的联盟，汇集了三个主要的研究 密歇根州的大学创建了一个新的全州范围的倡议：密歇根大学（U-M），密歇根州 大学（MSU）和韦恩州立大学（WSU）。这项建议的范围仍然完全在 密歇根州ADRC的目标是"促进，催化和执行AD和 相关的神经退行性疾病"，特别是密歇根州ADRC的临床核心目标，以"提高 老年痴呆症研究的多样性。在我们成功的基础上，我们将建立一个拉丁裔队列远程 密歇根州大急流城的招生点。为了实现这一目标，我们建议：1）利用现有的 社区伙伴关系，通过社区卫生培训解决ADRD中的健康差距 社区卫生保健诊所的工作人员和人员对认知障碍的早期迹象，2）增加 社区居住的拉丁裔老年人参与ADRD研究，3） 社区居住的老年拉丁美洲成年人有和没有认知障碍。最终目标是建立 一个有代表性的拉丁裔群体，提高拉丁裔在ADRD研究的地理代表性。 重要的是，使用健康公平框架，我们将建立一个社区居住的老年拉丁裔队列， 在服务不足的社区增加资源和获得医疗保健的机会， 重要的全州痴呆症为重点的资源，为研究人员，学员，医疗保健专业人员 及公众

ABSTRACT Health disparities in ADRD continue to be a major social and health justice challenge that affect the most vulnerable population in the USA. The fact that Black / African Americans and Latinos are more likely to not receive a dementia diagnosis and experience discrimination when visiting a physician indicates that disparity in ADRDs may be greater than estimated. The Michigan Alzheimer’s Disease Research Center (Michigan ADRC) was refunded in September 2021 as a tri-university consortium that brings together the three major research universities in Michigan to create a novel statewide initiative: University of Michigan (U-M), Michigan State University (MSU) and Wayne State University (WSU). The scope of this proposal remains well within the Michigan ADRC’s goal to “Foster, Catalyze and Perform Research of the Highest Potential Impact in AD and Related Neurodegenerative Disorders” and specifically for the Michigan ADRC’s Clinical Core aim to “Enhance Diversity in Aging and Dementia Research.” Building on our success, we will establish a Latino Cohort remote enrollment site in Grand Rapids, Michigan. To achieve this goal, we propose to 1) leverage established community partnerships to address health disparities in ADRD through the training of community health workers and personnel at community healthcare clinics about early signs of cognitive impairment, 2) increase participation of community dwelling older Latino adults in ADRD research, 3) profile plasma biomarker of community dwelling older Latino adults with and without cognitive impairment. The ultimate goal is to establish a representative Latino Cohort that enhances the geographical representation of Latinos in ADRD research. Importantly, using a Health Equity Framework, we will establish a community dwelling older Latino cohort while enhancing resources and access to healthcare within underserved communities and create a critically important statewide dementia-focused resource that serves researchers, trainees, health care professionals and the public.