RESEARCH CORE

MHDRC研究核心将增加关于少数群体健康的科学知识和意识 慢性病方面的健康差距，特别是在癌症筛查和糖尿病方面。研究和试点 在这一核心下资助的项目将集中于了解这些健康背后的机制 在这方面，我们将重点放在发展和测试干预措施上，以减少并最终消除差距。 具体来说，研究局将：1)监督三个全面发展的研究项目的进行；2)实施 试点项目方案，3)协助MHDRC调查人员开发和提交新的研究 外部资金项目，以及4)整合与少数群体有关的多个非政府组织专业知识来源 健康和健康差距研究，MHDRC和220多个教职员工组成其研究基地， 进行智力合作和持续研究。Catarina Kiefe，医学博士和Jamy Ard，医学博士，公共卫生硕士 领导研究核心。我们目前项目出口(方面)的经验已经产生了显著的效果 研究结果，特别是在结直肠癌筛查和糖尿病方面，并为 以社区为基础的干预非常成功。因此，MHDRC内的研究和试点项目 Research Core将以此为基础。第一个研究项目，《祖传遗传混合体》 新陈代谢综合征“，是一项观察性研究，将调查欧洲和非洲 胰岛素抵抗性状簇上的遗传混合体。第二个项目，“沟通能力培训” 少数族裔患者：改善结果的一种方式？？，是一项针对低收入人群的随机对照试验 少数民族糖尿病和高血压患者，检验是否有理论依据的干预教学 患者与医生的有效沟通将改善血糖和血压控制。第三 一项名为“教会干预增加癌症筛查”的研究项目使用了一种准实验方法。 旨在评估促进乳腺癌、宫颈癌和结直肠癌的多组分干预措施 对50岁以上的非裔美国女性进行筛查。最后，最初的试点项目“UCP3在脂肪中的作用” 非裔美国人(AA)女性的氧化“，是一个基因测序项目，将有助于 了解肥胖和糖尿病的种族差异。其他试点项目将通过以下方式获得资金 将MHDRC和慈善基金结合起来，实现了3个试点项目始终保持稳定状态。

The MHDRC Research Core will increase scientific knowledge and awareness about minority health and health disparities in chronic disease, specifically in cancer screening and diabetes. The research and pilot projects funded under this Core will concentrate on understanding the mechanisms underlying these health disparities, and on developing and testing interventions to reduce, and ultimately eliminate, them. Specifically, the RC will: 1) oversee the conduct of three fully developed research projects; 2) implement a pilot project program, 3) assist MHDRC investigators in the development and submission of new research projects for extramural funding, and 4) integrate multiple UAB sources of expertise pertinent to minority health and health disparities research with the MHDRC and the over 220 Faculty forming its research base, for intellectual collaboration and continued research. Catarina Kiefe, MD, PhD and Jamy Ard, MD, MPH will lead the Research Core. Experience from our current Project EXPORT (RESPECT) has produced notable findings, particularly in colorectal cancer screening and diabetes, and has provided a foundation for an extremely successful community-based intervention. Thus, the research and pilot projects within the MHDRC Research Core will be based on this foundation. The first research project, "Ancestral Genetic Admixture and the Metabolic Syndrome", is an observational study that will investigate the impact of European and African genetic admixture on the insulin resistance trait cluster. The second project, "Communication Training for Minority Patients: A Way to Improve Outcomes?", is a randomized controlled trial of ambulatory, low-income minority patients with diabetes and hypertension, testing whether a theory-grounded intervention to teach patients effective communication with physicians will improve glycemic and blood pressure control. The third research project, "A Church-Based Intervention to Increase Cancer Screening", uses a quasi-experimental design to evaluate a multi-component intervention to promote breast, cervical, and colorectal cancer screening in African American women over 50. Finally, the initial pilot project, "The Role of UCP3 in Fat Oxidation in African American (AA) women", is a gene sequencing project that will contribute to the understanding of racial differences in obesity and diabetes. Additional pilot projects will be funded through combined MHDRC and philanthropic funds to attain a "steady state" of 3 pilot projects at all times.