SOCA: LONGITUDINAL STUDY OF THE OCULAR COMPLICATIONS OF AIDS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项由美国国立卫生研究院资助的前瞻性、观察性、纵向研究的目的是在面对不断变化的抗HIV和抗CMV疗法的情况下，提供有关艾滋病眼部并发症的发生率和病程的信息。这项研究将监测巨细胞病毒视网膜炎和艾滋病其他眼部并发症的发病率的长期趋势；将确定HAART引起的免疫状态变化对巨细胞病毒视网膜炎和艾滋病其他眼部并发症风险的影响；将确定高危人群的特征；将评估治疗对视觉功能、生活质量和生存的影响。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objectives of this NIH-funded prospective, observational, longitudinal study is to provide information on the incidence and course of ocular complications of AIDS in the face of changing anti-HIV and anti-CMV therapies. The study will monitor secular trends in the incidence of CMV retinitis and other ocular complication of AIDS; will determine the effect of HAART-induced changes in immune status on the risk of CMV retinitis and other ocular complications of AIDS; will determine the characteristics of populations at high risk; and will evaluate the effects of treatments on visual function, QOL, and survival.