Science Education of Alcohol Metabolism

描述(申请人提供)：人类饮酒无处不在。虽然据报道，90%的人口消费不同数量的酒精，但只有一小部分人滥用酒精消费，但人数可观。据估计，10%-20%的男性和3%-10%的女性患有与酒精有关的持续性问题。年轻人饮酒仍然是我们国家关注的一个重要健康问题。青少年酗酒现象呈上升趋势，过度饮酒对个人、家庭和社会造成心理、社会和身体伤害。在拟议的第二阶段奖励期间，研究将完成，新的实验和试剂将在第三阶段的营销之前在车间和教室环境中进行测试。该公司在科学教育市场享有盛誉，以其高质量的产品、技术和教育服务以及具有竞争力的价格而享有良好声誉。这些评估将由讲习班参与者以及课堂学生和教师进行测试和使用。对学习评估的衡量将基于与两个学术教员的合作，以消除这些研究中可能存在的偏见。公共卫生相关性：青少年饮酒是我国重要的健康关注点，青少年酗酒现象呈上升趋势。过度饮酒会对个人、家庭和社会造成心理、社会和身体上的伤害。全国学龄儿童报告称，至少有一次发生过五杯或五杯以上的危险饮酒事件。青少年饮酒还会导致学业成绩不佳、参与犯罪和社会适应不良。同样令人担忧的是，有证据表明，早期饮酒与成人酗酒之间存在高度相关性。这项SBIR的目的是研究并在第三阶段向市场推出7至12年级的实验，以了解酒精是如何代谢的，以及个体之间的代谢率存在差异。

DESCRIPTION (provided by applicant): Human consumption of alcohol is ubiquitous. While it is reported that ninety percent of the population consumes various amounts of alcohol, only a small but sizable minority of the population abuse alcohol consumption. It is estimated that 10-20% of males and 3-10% of females develop persistent alcohol-related problems. Alcohol use by youth continues to be an important health focus for our Nation. Alcohol misuse among adolescents is on the increase, and excessive drinking is associated with psychological, social and physical harm to the individual, family and society. During the proposed Phase II award period, research will be completed and new experiments and reagents will be tested in workshop and classroom settings prior to the marketing in Phase III. The Company is well established in the science education market and enjoys a fine reputation for its high quality products, technical and education service, and competitive prices. The assessments will be tested and used by workshop participants and classroom students and teachers. Measurement of learning assessments will be based on collaborations with two academic faculty to remove possible bias in these studies. PUBLIC HEALTH RELEVANCE: Alcohol use by youth is an important health focus for our Nation and alcohol misuse among adolescents is on the increase. Excessive drinking is associated with psychological, social and physical harm to the individual, family and society. School age students nationwide report episodes of hazardous drinking of five or more drinks on at least one occasion. Adolescent drinking also leads to poor school performance, criminal involvement and social maladjustments. Equally alarming is evidence that suggests a high correlation between the early-onset of alcohol consumption and the development of alcoholism in adults. The aim of this SBIR is to research and in Phase III to market experiments for grades 7 to 12 on understanding how alcohol is metabolized and that there are differences in the rate of metabolism amongst individuals.