HIGH-THROUGHPUT X-RAY ABSORPTION SPECTROSCOPY

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该项目旨在进行高通量X射线吸收光谱（HTXAS）实施的技术开发。这些发展包括光束线对准、样品对准、数据采集策略、数据采集和分析的自动化和简化。 这些发展是针对一般用户社区以及通过将X射线吸收光谱作为蛋白质晶体学的补充工具来扩展结构基因组学的努力。 已进行可行性研究，以评估样本类型和样本保持器替代品。 斯科特教授今年在SSRL休假，继续担任该项目的负责人。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. TThis project is for technological developments for the implementation of High-throughput X-ray Absorption Spectroscopy (HTXAS). These developments include the automation and streamlining of beam line alignment, sample alignment, data acquisition strategies, data acquisition and analysis. The developements are targeted for the general user community as well as for the extension of structural genomics efforts by incorporation of x-ray absorption spectroscopy as a complementary tool to protein crystallography. Feasibility studies to assess sample types and sample holder alternatives have been performed. Prof. Scott, who spent a sabbatical leave at SSRL this year, contiues to be the lead of the project.