Career Development Component

职业发展 这项工作由詹姆斯·费拉米斯科博士领导。作为数字成像核心在癌症中的总监 他曾与大多数生物医学科学家互动，因此是最有见识的人 生物医学研究，特别是癌症研究的所有机会。他是个有用的人 在为克劳德·西林建立的职业发展和培训计划中，他是ICMIC的第一位现役实习生 (见第5a条)。美国国立卫生研究院资助的CREST项目是一个为期一到两年的项目，教授博士后和初级 教职员工如何进行临床研究和有效的拨款申请。这个项目在西林博士的 发展。事实上，在过去的两年中，佳洁士的毕业生中有3人在完成 他们的训练。我们在本提案后面的详细描述中介绍了Sirlin博士的计划，作为 培训计划课程会是什么样子。费拉米斯科博士将帮助学员选择量身定做的课程 他们的兴趣和需求，确定他们可以培训的实验室，并为他们指派一名导师 他们的实验室领导指引着他们的职业道路。他将得到ICMIC所有成员的帮助，在这一重要的 功能。我们将从加州大学圣迭戈分校接受培训的大量人员中招募人员，其中包括大约 500名医学博士和50名医学博士研究生，500名博士后研究员，300名博士生，600名实习生/住院医师和 预计招收240名药学博士，外加60名博士生和30名药房实习医生。因为我们相信一个 在扩大研究队伍方面，更关键和更重要的任务是从有前途的 本科生，我们希望吸引本科生，激发他们在医学研究方面的热情 继续进行研究生培训。在那些攻读研究生工作的人中，一些人将继续成为学者。 基础科学家和一些人将受到启发，接受医学/博士培训，成为临床科学家。通过 从本科阶段开始，我们将培养对科学感兴趣的人，而不是其他任何人 吸引并将创建一条新调查人员的管道。我们与加州大学圣地亚哥分校开展了合作 工程和生物工程部门及其领导人，这项工作已由 结合我们与NanoTUMOR中心的努力，为互动带来了大量的学生 来自物理科学的研究。此外，马特里也是最近被授予培训放射学的T32的私人侦探 将住院医生转变为临床科学家。伊莎贝尔·牛顿，医学博士/博士，Jamieson博士Dev项目的联合研究员 一个这样的人。癌症中心、纳米肿瘤中心和美国国家癌症研究所的职业发展使命 ICMIC与授予放射科的T32相结合应该会产生协同的积极影响 关于细胞和分子成像的努力。 职业发展工作的重点是主要集中在初级学院，以增加 加州大学圣迭戈分校ICMIC和博士后研究员的队伍，以增加训练有素的调查人员的队伍。 职业发展候选人将接受SRC的审查，他们的支持将是 或两年，取决于他们的培训水平和特定项目。他们将与一台基本的 科学和成像导师帮助指导他们的发展。临床科学家将得到支持，并将得到 需要将75%的时间投入到他们的研究培训中。

Career development This effort is lead by James Feramisco, PhD. As the director of the Digital Imaging core in the cancer center, he has interacted with most biomedical scientists and is therefore the most knowledgeable individual of all the opportunities available in biomedical research in general and cancer in particular. He was instrumental in the career development and training program established for Claude Sirlin, the first active trainee in ICMIC (See section 5a). The NIH-funded CREST program is a 1 or 2-year program that teaches postdocs and junior faculty how to conduct clinical research and effective grant writing. This program was invaluable in Dr. Sirlin's development. In fact, 3 of the CREST graduates in the past 2 years have won K awards by the completion of their training. We present Dr. Sirlin's program, in the detailed description later in this proposal as an example of what a training program curriculum would be like. Dr. Feramisco will help trainees select courses tailored to their interests and needs, identify laboratories where they can train, and assign them a mentor in addition to their laboratory leader to guide their career path. He will be aided by all ICMIC members in this important function. We will recruit from the large number of individuals in training at UCSD that include approximately 500 MD and 50 MD/PhD students, 500 postdoctoral fellows, 300 PhD students, 600 interns/resident and an expected enrollment of 240 Pharm.D. plus 60 PhD students and 30 pharmacy residents. Because we believe a more critical and important task in swelling the research ranks is to develop scientists from a promising pool of undergraduate students, we would like to attract undergraduates and excite them in medical science research to pursue postgraduate training. Of those that pursue graduate work, some will go on to become academic basic scientists and some will be inspired to pursue MD/PhD training and become clinician scientists. By starting from the undergraduate level, we will develop individuals with interest in science rather than any other lures and will create a pipeline of new investigators. We have developed collaborations with the UCSD Engineering and Bioengineering Departments and their leaders and this effort has been streamlined by combining our effort with the NanoTUMOR Center that brings to the interaction a large number of students from the physical sciences. In addition, Mattrey is also the P.I. of a recently awarded T32 to train radiology residents into clinical scientists. Isabel Newton, MD/PhD a co-investigator on Dr. Jamieson's Dev Project is one such individual. The Career Development missions of the Cancer Center, NanoTUMOR Center and the ICMIC in combination with the T32 awarded to the Dept of Radiology should have a synergistic positive impact on the cellular and molecular imaging effort. The emphasis of the Career Development effort is to focus primarily on Junior Faculty to increase the ranks of the UCSD ICMIC and then on postdoctoral fellows to increase the ranks of well trained investigators. Career Development candidates will be reviewed by the SRC for acceptance and their support will be for one or two years depending on their level of training and particular projects. They will be paired with a basic science and an imaging mentor to help guide their development. Clinical scientists will be supported and will be required to commit 75% of their time to their research training.