Alcohol-Related Risky Sex Prevention

描述(由申请人提供)：该指导研究科学家发展奖(K01)的目的是开发一个关于高风险饮酒和性行为的病因学和预防的独立研究计划。这一目标将通过五年指导培训计划和补充研究计划来实现。培训计划的目的是：1)增加酒精使用的病因和预防以及相关问题的知识；2)获得纵向和实验方法方面的经验；3)获得多元统计技术的知识和经验；4)加强手稿和资助写作技能。目标将通过互动式指导培训计划实现，该计划包括正式课程、研讨会、讲习班、全国会议和撰写一份重要评论。拟议的研究将扩大通过培训计划获得的知识。这项研究的长期目标是减少大学生的饮酒、与酒精相关的危险性行为及其负面后果。这项研究的具体目标将通过三个不同的研究来实现。研究1包括一项旨在实现具体目标1的横断面研究，该研究旨在记录校园饮酒和性行为规范及其与个人行为的关系。研究二将采用2(饮酒个性化规范反馈)×2(酒精相关危险性行为)6个月的纵向实验，以达到特定的目标2-3。具体目标2是评估PNF在减少饮酒、与酒精相关的危险性行为及其负面后果方面的效果。具体目标3将评估干预背后的理论机制。研究3将采用2(酒精)×2(PNF)实验设计来实现特定目标4，即评估酒精相关危险性行为和酒精中毒对酒精相关危险性行为可能性的影响。玛丽·拉里默博士、珍妮特·诺里斯博士和威廉·乔治博士将担任这一奖项的导师，并将提供酒精使用、性风险和实验方法方面的专业知识。华盛顿大学的资源为发展酒精研究事业和开展拟议的研究提供了有利的环境。该奖项将允许申请者获得必要的知识和技能，成为独立的研究员，并向国家酒精滥用和酒精中毒研究所提出R01拨款申请。

DESCRIPTION (provided by applicant): The purpose of this Mentored Research Scientist Development Award (K01) is to develop an independent program of research on the etiology and prevention of high-risk alcohol use and sexual behavior. This goal will be achieved via a five-year mentored training plan and complementary research plan. Aims of the training plan are to: 1) increase knowledge of the etiology and prevention of alcohol use and related problems, 2) gain experience in longitudinal and experimental methodology, 3) gain knowledge of and experience with multivariate statistical techniques, and 4) strengthen manuscript and grant writing skills. Goals will be achieved through an interactive mentored training plan comprised of formal coursework, seminars, workshops, national conferences, and writing a major review. Knowledge gained via the training plan will be augmented by the proposed research. The long-term goal of this research is to reduce alcohol consumption, alcohol-related risky sex, and their negative consequences among college students. Specific aims of this research will be accomplished in three distinct studies. Study 1 consists of a cross-sectional study designed to achieve specific aim 1, which is to document campus norms for drinking and sexual behavior and their relation to personal behavior. Study 2 will employ a 2 (drinking personalized normative feedback (PNF)) x 2 (alcohol-related risky sex PNF) 6-month longitudinal experimental designed to achieve specific aims 2-3. Specific aim 2 is to evaluate the efficacy of PNF in reducing alcohol consumption, alcohol related risky sex, and their negative consequences. Specific aim 3 will evaluate the theoretical mechanisms underlying the intervention. Study 3 will employ a 2 (alcohol) x 2 (PNF) experimental design to achieve specific aim 4, which is to evaluate the affect of alcohol-related risky sex PNF and alcohol intoxication on likelihood of alcohol-related risky sex. Drs. Mary Larimer, Jeanette Norris, and William George will serve as mentors on this award and will provide expertise in alcohol use, sexual risk, and experimental methodology. Resources at the University of Washington provide an environment conducive to developing a career in alcohol research and for conducting the proposed research. This award will allow the applicant to gain the knowledge and skills necessary to become and independent researcher and develop a R01 grant application with the National Institute on Alcohol Abuse and Alcoholism.