WNPRC AGING COLONY RESOURCE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 维持一个老年恒河猴群体，作为衰老相关研究的专门资源。 资源访问的分配 WNPRC拥有约90只20岁以上的恒河猴。国家衰老研究所提供部分支持，以维持这些动物用于与正常衰老有关的研究。在2007 -2008财年期间，约20名研究者在与神经内分泌学、热量限制、葡萄糖代谢、卵巢功能障碍、骨密度、骨关节炎、免疫学、眼科学、肿瘤学和生殖学相关的研究中使用了这些动物。没有拒绝任何请求。 传播 通过在同行评审期刊上发表文章和出席科学会议，向科学界传播知识。威斯康星州国家灵长类动物研究中心还举行季度研究务虚会，以增加各种服务和资源单位之间的沟通。 进展 在本报告年度，约20名研究者使用了老化群体的动物。 我们继续监测殖民地所有动物的健康状况，并对一般饲养地的老龄个体进行评价，以评价其是否适合纳入老龄饲养地。 亮点 老年恒河猴资源中的动物继续得到良好的医疗照顾。在种群中，目前有四个非常老的个体（超过30岁）。 挑战 与这种资源相关的主要挑战是保持适当大小的健康群体以满足科学需求。 关切 没有一 培训 在既定的方案中提供食物摄入量测量、身体成分评估、身体活动监测、认知和运动技能评估以及代谢评估等培训。 在过去一年中，在所有这些领域开展了培训。 出版物说明：老龄化资源支持涉及许多部分或全部依赖WNPRC资源的期刊文章。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To maintain an aged rhesus macaque colony as a specialized resource for studies relating to aging. Allocation of Resource Access The WNPRC has approximately 90 rhesus monkeys over 20 years of age. Support is provided in part by the National Institute of Aging to maintain these animals for studies relating to normal aging. During FY2007-2008, approximately 20 investigators used these animals in studies related to neuroendocrinology, calorie restriction, glucose metabolism, ovarian dysfunction, bone mineral density, osteoarthritis, immunology, ophthalmology, oncology and reproduction. No request has been denied. Dissemination Knowledge is disseminated to the scientific community via publications in peer reviewed journals and scientific meeting attendance. The Wisconsin National Primate Research Center also holds quarterly research retreats to create increased communication between the various service and resource units. Progress During the current reporting year, approximately 20 investigators have utilized animals from the aging colony. We continue to monitor the health and well-being of all animals in the colony and evaluate aging individuals from the general colony to evaluate their appropriateness for inclusion in the aging colony. Highlights The animals in Aged Rhesus Monkey Resource continue to receive excellent medical attention. Within the population, there are currently four very old (greater than 30 years) individuals. Challenges The major challenge associated with this resource is maintaining a healthy colony of an appropriate size to meet scientific need. Concerns None Training Training is available in established protocols food intake measurement, body composition assessment, physical activity monitoring, cognitive and motor skills assessment, and metabolic assessments. Training in all of these areas was carried out during the past year. Publications note: Aging Resource support is involved in numerous journal articles that depend in part or in full on WNPRC resources.