CLINICAL TRIAL: TAI CHI FOR DIASTOLIC HEART FAILURE

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究的主要目的是确定与社区有氧运动计划相比，舒张性心力衰竭（DHF）患者定制的12周太极拳计划的安全性和可行性。本研究还将估计每组的运动强度，探讨两种运动的心理和生理反应，并提供初步的成本估计。 这是一项纳入20例患者的前瞻性、随机对照初步试验。结果测量包括运动能力、健康相关的生活质量、情绪、运动自我效能、血清B型利钠肽水平、超声心动图分析、心率变异性和自主神经张力。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary purpose of this study is to determine the safety and feasibility of a tailored 12-week tai chi program in patients with diastolic heart failure (DHF) as compared to a community-based aerobic exercise program. This study will also estimate exercise intensity of each group, explore psychosocial and physiological responses to both exercises and provide preliminary estimates of cost. This is a prospective, randomized controlled pilot trial of 20 patients. Outcome measurements include exercise capacity, health related quality-of-life, mood, exercise self-efficacy, serum B-type natriuretic peptide levels, echocardiographic analysis, heart rate variability and autonomic tone.