BIOBEHAVIORAL MECHANISMS OF EMOTION IN HIV DISEASE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 积极情绪与皮质醇水平呈负相关，与消极情绪的影响无关。 第二章：积极情绪将与积极的健康行为概况相关，因此它将直接与药物依从性，身体活动和吃健康食品相关，并与吸烟，饮酒，吸毒和性风险行为呈负相关，独立于消极情绪的影响。 3：。积极情绪与病毒载量、HIV疾病症状和一般症状呈负相关，与CD 4+直接相关，与消极情绪的影响无关。 第四章：积极情绪和健康指标之间的关系将部分介导的皮质醇水平和健康行为，独立的负面情绪的影响。 第五节：负性情绪与皮质醇、健康行为和健康指标的关系与正性情绪相反，且负性情绪与健康指标的关系部分由皮质醇和健康行为介导。 6：积极情绪会缓和消极情绪的影响。 本研究的主要目的是阐明积极情绪与HIV感染者健康之间的关系，并评估积极情绪和消极情绪是否通过生物学和行为机制与HIV感染者健康相关。本研究还将试图确定积极情绪是否独立于消极情绪或通过与消极情绪的相互作用与健康相关。由于情绪对慢性病样本健康的影响可能是慢性的，而不是暂时的，行为实践和神经内分泌过程的结果，目前的研究将集中在特质的影响，而不是状态，情绪。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Positive emotion will relate inversely to cortisol levels, independent of the effects of negative emotion. 2: Positive emotion will relate to a positive health behavior profile such that it will directly relate to medication adherence, physical activity, and eating healthy foods and will inversely relate to smoking, alcohol use, drug use, and sexual risk behavior, independent of the effects of negative emotion. 3:. Positive emotion will inversely relate to viral load, HIV disease symptoms, and general symptoms and will directly relate to CD4+, independent of the effects of negative emotion. 4: The relation between positive emotion and health indicators will be partially mediated by cortisol levels and health behaviors, independent of the effects of negative emotion. 5: Negative emotions will relate to cortisol, health behaviors, and health indicators in the opposite direction from positive emotion, and the relation between negative emotion and health indicators will be partially mediated by cortisol and health behaviors. 6: Positive emotion will moderate the effects of negative emotion. The primary goal of the current study is to clarify the relation between positive emotion and health in persons with HIV disease and to evaluate whether both positive and negative emotions relate to health in persons with HIV disease via biological and behavioral mechanisms. This study will also seek to establish whether positive emotions relate to health independent of negative emotions or through interaction with negative emotion. Because the impact of emotions on health in chronic illness samples is likely to be a result of chronic, rather than momentary, behavioral practices and neuroendocrine processes, the current study will focus on the effects of trait, rather than state, emotion.