Clinical Research and Assay Support

临床研究核心负责处理目前正在进行的大量临床研究中的人体样本。一旦采集到样本，我们就会根据规程上的说明进行处理，并根据首席调查员的指示对样本进行等量、标记和储存。我们目前平均每周处理986个样品。在实验室处理的所有样品都设置了跟踪号，并输入了由Core实验室维护的数据库。自2008年1月开始的研究使用我们实验室开发的2D条形码系统进行标记。核心实验室还与费希尔生物服务公司建立了一项生物储存库服务，用于长期非现场存储样本。 除了PIS的生物储存库需求外，临床研究核心还为DLM目前无法提供的分析提供分析服务。我们已经测试和验证了多种方法来检测人类血浆中总的和活性的Glug样肽-1、酰基Ghrelin、Desacyl Ghrelin、Leptin、脂联素、Oxyntomodrin和其他几种标志物。

The Clinical Research Core is responsible for processing human samples from numerous clinical studies currently in progress. Once the samples are acquired we process it according to the instructions on the protocol, aliquot, label and store the samples for the various principal investigators as per their instructions. We are currently processing an average of 986 samples/week. All samples processed in the lab are set up with a tracking number and entered into a database which is maintained by the Core lab. Studies that have started since January 2008 are labeled using a 2D-barcode system developed in our lab. The Core lab has also set up a biorepository service with Fisher Bioservices for long term off-site storage of samples. In addition to the biorepository needs of the PIs, the Clinical Research Core also provides assay services for analyses which are currently not available at DLM. We have tested and validated numerous methods to measure total and active Glucagon-like Peptide-1, Acyl Ghrelin, Desacyl Ghrelin, Leptin, Adiponectin, Oxyntomodulin and several other markers in human plasma.