Biostatistics and Biomechanical Measurement Core

生物统计和生物力学测量核心（BBMC）将为SCOR项目I，II和III提供生物统计和生物力学支持。 AIM 1旨在协助研究设计、把握度分析和数据分析计划。 AIM 2是为实验、临床和三维成像测量提供工程支持。 AIM 3是为SCOR项目之间的数据库管理和信息交换提供支持。 目标4是在SCOR项目中进行高质量的统计分析， 目标5是结合核心C，为年轻的研究人员提供这些方法的指导和培训。 核心B将协助项目1（30具尸体）中组织特性和定量组织学测量的技术方面，以及项目1中人类受试者测量（n=60）。在项目11中，它将协助对多达88名妇女的耻骨内脏肌及其MR图像缺陷进行产后量化。在项目111中，它将使用生物力学仪器、标准化3-D MR图像和临床测量来帮助测量多达100名妇女的阴道支撑。最后，核心B将继续促进新的学术合作，并与行业合作伙伴的接口，开发新的仪器和分析技术的需要。

The Biostatistical and Biomechanical Measurements Core (BBMC) will provide biostatistics and biomechanical support to SCOR Projects I, II, and III. AIM1 is to assist with study design, power analyses and data analysis plans. AIM 2 is to provide engineering support for experimental, clinical and 3-D imaging measurements. AIM 3 is to provide support for database management and information exchange across SCOR Projects. AIM 4 is to conduct high quality statistical analyses across SCOR Projects, and AIM 5 is to provide mentoring and training of young investigators in these methods in conjunction with Core C. Core B will assist with technical aspects of tissue property and quantitative histology measurements in Project 1 (30 cadavers), as well as human subjects measurements (n=60) in Project 1. In Project 11 it will assist with post-natal quantification of pubovisceral muscles and their defects in MR images from up to 88 women. In Project 111 it will assist with measurements of vaginal support using biomechanical instrumentation, standardized 3-D MR images and clinical measurements in up to 100 women. Finally, Core B will continue to foster new academic collaborations and interface with industry partners, developing novel instrumentation and analytical techniques as needed.