CANCER CONTROL

项目总结(见说明)： 癌症控制(CC)计划的科学目标是促进以人群为基础的研究，以降低南卡罗来纳州(SC)的癌症发病率和死亡率，同时提供科学证据和可应用于该州境外的新型癌症控制干预措施。CC项目调查员主要通过在两个主要主题--产生烟草控制的新见解和方法以及解决癌症健康差距--方面的重点研究工作，朝着这一目标取得了实质性进展。在这两个主题下，CC计划成员通力合作，进行研究并将其联系起来，以确定导致个人患癌症的行为风险因素，并将这些发现转化为具有成本效益的可持续干预措施，以修改风险因素。此外，CC计划成员正在与政府和社区领导人合作，传播这些基于证据的战略，以影响SC的癌症负担。目前，CC计划由23名成员组成，代表医学院、护理学院和药学院内的11个系，拥有超过460万美元的同行评议的校外研究资金(NCI提供160万美元)，以及另外64万美元的计划支持培训和职业发展奖励。在过去五年中，计划成员出版了170份出版物，其中17%是计划间合作，29%是计划内合作，57%是多机构合作。

PROJECT SUMMARY (See instructions): The scientific goal of the Cancer Control (CC) Program is to foster population-based research that will lead to a reduction in cancer morbidity and mortality in South Carolina (SC) while providing scientific evidence and novel cancer control interventions that can be applied beyond the state's borders. The CC Program investigators have made substantive progress toward this goal primarily through focused research efforts in two major themes - generating novel insights and approaches to tobacco control and addressing cancer health disparities. Within these two themes, the CC Program members work collaboratively to conduct and link research that identifies behavioral risk factors predisposing individuals to cancer development and to translate these findings into cost effective, sustainable interventions to modify risk factors. Furthermore, the CC Program members are working with government and community leaders to disseminate these evidence based strategies to impact the cancer burden in SC. Currently, the CC Program consists of 23 members representing 11 departments from within the College of Medicine, College of Nursing and the College of Pharmacy with more than $4.6M in peer-reviewed extramural research funding ($1.6M from the NCI) and another $640K in program-supportive training and career development awards. In the past five years, program members produced 170 publications with 17% of these representing inter-programmatic and 29% intra-programmatic collaborations, and 57% from multi-institutional collaborations.