Strengthening Research Administration Infrastructure for HIV Research in Nigeria

计划摘要 尼日利亚是世界上艾滋病毒流行最严重的国家之一，有180万艾滋病毒携带者。这个 美国政府在尼日利亚的艾滋病毒护理和研究方面进行了巨额投资，通过 总统艾滋病紧急救济基金(PEPFAR)支持的项目和国家艾滋病研究所 卫生(NIH)研究培训赠款，支持尼日利亚大学的研究人员培训。 尼日利亚的艾滋病毒研究对艾滋病毒的管理、治疗和预防做出了重大贡献 在该国，以及在世界范围内制定国际准则。尼日利亚大学恩苏卡 联合国大学医学院实施了多个艾滋病毒研究项目，主要是作为次级获奖者。发现 我们对84名联合国研究人员和研究管理人员进行的快速需求评估表明，93%的 研究人员表示有兴趣提交拨款申请，包括艾滋病毒研究，但只有28%的人知道 在联合国与谁联系以获得提案和提交支持。使联合国能够成功提交和管理赠款 申请作为首屈一指的院校，有必要加强其科研行政管理 基础设施。本提案的目标是：1)进一步确定研究管理方面的需求和差距 和联合国的管理；2)改善赠款管理和提案制定知识和技能 联合国研究管理人员和艾滋病毒执行研究人员；以及3)加强联合国的能力 研究管理员和艾滋病毒实施研究人员提交和管理成功的艾滋病毒赠款 通过提供导师、持续指导和加州大学圣迭戈分校项目讲师的在线课程来申请。加州大学 圣地亚哥研究管理和赠款管理方面的专家将落实 拟议的基础设施发展培训计划。拟议的计划将由格雷戈里·亚伦斯博士领导， 加州大学圣地亚哥分校奥特曼临床和翻译研究所教授兼主任传播和 实施科学中心(DISC)担任项目主任，Echezona Ezeanolue教授和 联合国翻译和实施研究中心主任(CTAIR)担任联席主任。Aarons博士和 Ezeanolue拥有现有的关系和在尼日利亚机构建设能力的丰富经验 通过尼日利亚实施科学联盟(NISA)。一个由研究管理和拨款组成的团队 加州大学圣地亚哥分校的管理专家将对研究管理员进行培训并提供持续的指导 并为联合国的管理人员提供为期3年的补助金。在本次基础设施开发培训结束时 计划，12名联合国研究管理员和赠款经理将能够成功地提交和管理 NIH、疾病控制和预防中心(CDC)和其他资助的艾滋病毒赠款。

Program Summary Nigeria has one of the largest HIV epidemics in the world with 1.8 million people living with HIV infection. The United States government has made huge investments in HIV care and research in Nigeria, through the Presidents Emergency Funds for AIDS Relief (PEPFAR)-supported programs and the National Institutes for Health (NIH) research training grants that have supported the training of researchers in Nigerian universities. Research on HIV in Nigeria has contributed significantly to the management, treatment, and prevention of HIV in the country as well to the development of international guidelines worldwide. The University of Nigeria Nsukka (UNN) College of Medicine has implemented multiple HIV research projects mostly as a sub-awardee. Findings from our rapid needs assessment with 84 UNN researchers and research administrators indicated that 93% of researchers expressed interest in submitting grant applications, including for HIV research, but only 28% knew who to contact for proposal and submission support at UNN. For UNN to successfully submit and manage grant applications as a prime institution, there is need to strengthen its research administration and management infrastructure. The objectives of this proposal are to: 1) further identify needs and gaps in research administration and management at UNN; 2) improve the grants management and proposal development knowledge and skills of UNN research administrators and HIV implementation researchers; and 3) strengthen the ability of UNN research administrators and HIV implementation researchers to submit and manage successful HIV grant applications by providing mentorship, ongoing coaching and online courses from UCSD program instructors. UC San Diego experts in research administration and grant management will implement the objectives of the proposed infrastructure development training program. The proposed program will be led by Dr. Gregory Aarons, Professor and Director of UC San Diego Altman Clinical and Translational Research Institute Dissemination and Implementation Science Center (DISC) as Program Director, and Dr. Echezona Ezeanolue, Professor and Director of UNN Centre for Translation and Implementation Research (CTAIR) as Co-Director. Drs. Aarons and Ezeanolue have an existing relationship and extensive experience building capacity in Nigerian institutions through the Nigeria Implementation Science Alliance (NISA). A team of research administration and grant management experts from UC San Diego will train and provide ongoing mentoring to research administrators and grant management staff at UNN over a 3-year period. By the end of this infrastructure development training program, 12 UNN research administrators and grant managers will be able to successfully submit and manage NIH, Centers for Disease Control and Prevention (CDC) and other funded HIV grants.