Developmental and Mentoring Core

摘要：发展核心 北卡罗来纳州-马拉维-南非癌症联盟(UMSACC)寻求培训下一代 从业者和领导者将在中低度地区开展艾滋病毒相关恶性肿瘤的高影响力研究 收入国家(LMIC)设置。我们建议的发展和指导核心(发展核心)将 嵌入现有的、非常成功的、由美国国立卫生研究院支持的研究培训基础设施中 在过去的二十年里与马拉维和南非的LMIC合作伙伴建立了合作伙伴关系。尽管我们有很多人 培训的成功，LMIC环境中的调查人员的一个中心问题是缺乏敬业的职业 发展支持和受保护的时间进行研究和竞争独立的资金。我们 建议通过对职业生涯早期进行培训和指导的综合方法来解决这一问题 癌症研究人员。首先，我们将创建一个强大的导师计划，以支持至少 九名非洲和美国调查人员。导师将专注于设计和实施假设驱动的 研究、手稿写作和发展助学金。第二，我们将利用持续的领导力 马拉维和南非的发展方案，以培养一支强大的研究监督员/导师队伍 面向医学和公共卫生实习生。第三，我们将提供至少15项有指导意义的研究资助给有希望的 非洲和美国调查人员支持假说驱动的研究项目和/或获得初步数据 与艾滋病毒相关的恶性肿瘤相关的更大的赠款申请。

ABSTRACT: DEVELOPMENTAL CORE The UNC-Malawi-South Africa Cancer Consortium (UMSACC) seeks to train the next generation of practitioners and leaders to conduct high-impact research on HIV-Associated malignancies in low- and middle- income country (LMIC) settings. Our proposed Developmental and Mentoring Core (Developmental Core) will be embedded within the existing, highly successful, NIH-supported research training infrastructure that UNC has established with LMIC partners in Malawi and South Africa over the past two decades. Despite our many training successes, a central problem for investigators in LMIC settings is the lack of dedicated career development support and protected time to conduct research and compete for independent funding. We propose to address this problem through a comprehensive approach to training and mentoring early-career cancer researchers. First, we will create a strong mentorship program to support the development of at least nine African and U.S. investigators. Mentorship will focus on design and implementation of hypothesis-driven research, manuscript writing, and development of grants. Second, we will leverage ongoing leadership development programs in Malawi and South Africa to develop a strong pool of research supervisors/mentors for medical and public health trainees. Third, we will provide at least 15 mentored research grants to promising African and U.S. investigators to support hypothesis-driven research projects and/or obtain preliminary data for larger grant applications related to HIV-associated malignancies.