T32 Training Program in Diabetes Translational Research

项目摘要 2型糖尿病的发病率和患病率继续上升。尽管增长和强劲的 临床试验证据基础上，大多数患者没有达到所有循证护理的目标。这 临床证据和临床实践之间的“第二个翻译障碍”是导致 糖尿病中可避免的发病率和死亡率。这本T32糖尿病翻译的首要目标 研究性培训计划是培养有动力的优秀博士后医学博士和博士 具有将证据转化为2型糖尿病患者实践所需技能的研究人员 和糖尿病前期。我们将每年招收一名博士后实习生，为期两年的培训经验， 因此，在第一年之后，每年支持2名受训人员。培训计划将设在德皇酒店 常设研究部，将与来自 加州大学伯克利分校医学院和加州大学伯克利分校公共卫生学院。理查德博士联合执导 授予医学硕士学位和朱莉·施密特迪尔博士博士学位，这个T32项目包括16名主要研究人员 目前有2,400万美元研究经费的导师和另外23名中学教师导师 具有跨学科的专业知识，为学员提供支持。该计划提供了一个机会， 在集成的护理系统、高级课程中嵌入有指导的研究学徒 加州大学旧金山分校和加州大学伯克利分校的实施科学和统计研究方法(包括 公共卫生硕士学位的选项)，以及一个由研究和职业导师组成的协调团队来指导学员 面向未来的学术研究事业。我们将在强大的协作关系基础上与 与我们在加州大学旧金山分校和加州大学伯克利分校的学术伙伴合作。的关键要素 研究性培训包括强有力的指导；体验式、小组和正规课程学习；以及 用于研究的强大的综合电子健康记录数据。

Project Abstract Type 2 diabetes continues to increase in incidence and prevalence. Despite a growing and robust clinical trial evidence base, the majority of patients do not meet all evidence-based goals of care. This “Second Translational Block” between clinical evidence and clinical practice is a major contributor to avoidable morbidity and mortality in diabetes. The overarching goal of this T32 Diabetes Translational Research training program is to prepare motivated and outstanding post-doctoral MD and PhD researchers with the necessary skills to translate evidence into practice for patients with type 2 diabetes and pre-diabetes. We will recruit one post-doctoral trainee each year for a 2-year training experience, thus supporting 2 trainees per year after the first year. The training program will be based at the Kaiser Permanente Division of Research and will be conducted in collaboration with research faculty from the UCSF School of Medicine and the UC Berkeley School of Public Health. Co-directed by Dr. Richard Grant MD MPH and Dr. Julie Schmittdiel PhD, this T32 program includes 16 primary research faculty mentors with $24 million in current research funding and an additional 23 secondary faculty mentors with cross-disciplinary expertise to support trainees. The program provides the opportunity for a mentored research apprenticeship embedded within an integrated care system, advanced coursework in implementation science and statistical research methods from UCSF and UC Berkeley (including the option for an MPH degree), and a coordinated team of research and career mentors to guide trainees towards future academic research careers. We will build on our strong collaborative relationships with health care systems and with our academic partners at UCSF and UC Berkeley. Key elements of the research training include strong mentorship; experiential, small group, and formal course learning; and robust integrated electronic health record data for research.